multiple— 多工 · 复式 ascend— 登 · 升腾 · 跻 · 擢升 · 升高 · 陟 dose名— 剂名 · 剂量名 · 用量名 查看更多用例•查看其他译文 查看其他译文 © Linguee 词典, 2024 ▾ 外部资源(未审查的) A phaseIb(multiple ascending doses)study will be ...
Two-Part Phase 1 Multiple-Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of TRV734 in Healthy Adultsanalgesicbiased ligandopioidTRV734TRV734, an oral G-protein biased ligand at the 渭-opioid receptor has demonstrated differentiated pharmacology in ...
5 Clinically, a multiple ascending-dose (MAD) phase 1b study was completed in participants with mild AD, with the primary objective of evaluating the safety and tolerability of BIIB080. As previously published,6 BIIB080 was generally well tolerated. The majority of adverse events were mild or...
The initial results from Design’s Phase 1 multiple ascending dose trial underscore the promise of DT-216 as a potential disease-modifying treatment for FA. The favorable systemic safety profile and FXN response support continued development of DT-216. However, the company has elected to complete ...
Rallybio Corporation (Nasdaq: RLYB) today announced preliminary Phase 1 multiple ascending dose (MAD) data for RLYB116, an innovative, long-acting, lo
We then completed a placebo-controlled, randomized, double-blind, multiple ascending-dose phase 1 study (NCT03538743), in which we enrolled 98 patients with T2D on background metformin and randomized them to receive multiple ascending doses of danuglipron or placebo for 28 d, across eight ...
Zealand Pharma A/S announced results from Part 1 of a multiple ascending dose trial for ZP8396, the company's long-acting amylin analog with potential for the management of overweight and obesity.
The PK of the active metabolite, RO7011785, increased linearly with dose from 40mg to 170mg. There was no PK accumulation following QOD dosing. The PK profile is consistent with observations in white subjects in the global first-in-human study. Single and multiple doses of RO7020531 resulted...
Regulus Therapeutics Announces First Patient Dosed in Third Cohort of Phase 1b Multiple-Ascending Dose (MAD) Clinical Trial of RGLS8429 for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Published Nov 2, 2023 8:00am EDT SAN DIEGO, Nov. 2, 2023 /PRNewswir...
The objectives of these studies were to evaluate zilurgisertib pharmacokinetics, safety, tolerability, and the effect of food in healthy participants from phase 1 single ascending dose (SAD) and multiple ascending dose (MAD) studies. Methods Both the SAD and MAD studies were double-blind, ...