Diverse human tumors obtained directly from surgery or biopsy can grow at high frequency in 3-dimensional Gelfoam® histoculture for long periods of time and still maintain many of their in vivo properties. The in vivo properties maintained in vitro in
To date over 250 patients have been treated with 131I-chTNT-3 demonstrating that all types of tumors can be targeted without significant uptake in normal tissues. TNT fusion proteins therefore have unique promise as second generation agents for the immunotherapy of solid tumors....
et al. Leukocyte-facilitated tumor dissemination: findings from multiple types of human tumors. J Cell Biochem. 2011; 112 (4):1154–67.Man YG, Mason J, Harley R, Kim YH, Zhu K, Gardner WA. Leukocyte-mediated cell dissemination and metastasis: findings from multiple types of human tumors....
These tumors start outside the bone marrow in the body's soft tissues. Usually, they happen in your throat, sinuses, nose, and larynx (or voice box). Up to 30% of people with extramedullary plasmacytomas will get multiple myeloma. Treatment involvesradiation therapy, surgery, or both. 5. ...
"The next steps will be looking at its efficacy, in terms of how robust it is in actually shrinking a tumor or causing a clinical response," Zaidi continued. Two trials already are underway using this technology, one with brain tumors and another with bladder cancer, Marron said. ...
Immunotherapy shows promise for positively changing the landscape of the management of many advanced solid tumors, including gastrointestinal (GI) malignan... AG Murphy,L Zheng - 《Human Vaccines》 被引量: 7发表: 2015年 Denileukin diftitox reduces EL4 lymphoma growth by depleting regulatory T cel...
Therefore, these models are a valuable representation of real glioblastoma tumors and provide resources to find new therapeutic targets. 3.3.3 Other types of cancer Ovarian cancer has not been frequently explored with 3D bioprinting, although models comprising ovarian cancer cells (OVCAR5) co-cultured...
MCED tests represent a potential new approach to detecting signals for multiple cancer types by utilizing cell-free DNA (cfDNA) or other circulating analytes in the blood shed by tumors. As such, CCGA study investigators sought to develop and utilize a MCED test to detect cancer ...
Multiple gastrointestinal stromal tumors (GISTs) are extremely rare and usually associated with type 1 neurofibromatosis and familial GIST. The aim of this study was to investigate the clinical, phenotypic, and genetic characteristics of multiple GISTs to gain insights into their underlying pathogenesis ...
Solid Tumors By Jo Cavallo/December 10, 2024 The Future of Cancer Care, Part 2 The soaring number of cancer survivors since the National Cancer Act of 1971 was enacted into law provides a snapshot of the profound progress made against cancer over the past half-century: 3 million survivors ...