A fast and sensitive multiple sequence alignment algorithm A two-step multiple alignment strategy is presented that allows rapid alignment of a set of homologous sequences and comparison of pre-aligned groups of se... M Vingron,P Argos - 《Computer Applications in the Biosciences Cabios》 被引...
(2006). Multiple Sequence Alignment as a Workbench for Molecular Systems Biology, Current Bioinformatics 1 : 95- 104.Thompson JD, Poch O.(2006). Multiple sequence alignment as a workbench for molecular systems biology,Curr Bioinformatics , 1:95-104....
MultipleMultipleSequenceSequence AlignmentAlignment LuonanChenLuonanChen OsakaSangyoUniversityOsakaSangyoUniversity Chapter-4 ApplicationsApplications •Genomesequencing •Protein:conservedfunctionalor structuraldomains •DNA:structuralandfunctional relationships,promoter,bindingsite •Biotech:specificprobe,PCRprimer •...
The multiple sequence alignment is a well known tool in the field of molecular biology. It has wide range of applications that include finding the characteristic motifs among biological sequences, backtracking the evolutionary paths through sequence similarity, identifying the ...
Our results suggest that HelixFold-Single performs well in predicting flexible regions of these proteins, highlighting its strengths for such applications. HelixFold-Single HelixFold-Single aims to take advantage of both the PLM and the main modules used in AlphaFold2 for single-sequence-based ...
A standard procedure in many areas of bioinformatics is to use a multiple sequence alignment (MSA) as the basis for various types of homology-based inference. Applications include 3D structure modelling, protein functional annotation, prediction of molecular interactions, etc. These applications, however...
Protein structure prediction pipelines based on artificial intelligence, such as AlphaFold2, have achieved near-experimental accuracy. These advanced pipelines mainly rely on multiple sequence alignments (MSAs) as inputs to learn the co-evolution informa
Multiple sequence alignment is increasingly important to bioinformatics, with several applications ranging from phylogenetic analyses to domain identification. There are several ways to perform multiple sequence alignment, an important way of which is the progressive alignment approach studied in this work. ...
J Kim,JR Cole,S Pramanik - 《Computer Applications in the Biosciences Cabios》 被引量: 61发表: 1996年 Multiple sequence alignment using a genetic algorithm The conventional multiple sequence alignment algorithms are classi ed into two categories: iterative improvement strategies (e.g., [1]) and...
Learning to Paraphrase: An Unsupervised Approach UsingMultiple-Sequence AlignmentRegina Barzilay and Lillian LeeDepartment ofComputer ScienceCornell UniversityIthaca, NY 14853-7501regina,llee @cs.cornell.eduAbstractWe address the text-to-text generation prob-lem of sentence-level paraphrasing — a phe-nom...