Multiple sequence alignment as a workbench for molecular systems biology. Curr Bioinformatics. 2006; 1 :95–104.Thompson, J. and Poch, O. (2006). Multiple Sequence Alignment as a Workbench for Molecular Systems Biology, Current Bioinformatics 1 : 95- 104....
multiple sequence alignment, combinatorial optimizations 1 Introduction The multiple sequence alignment is a well known tool in the field of molecular biology. It has wide range of applications that include finding the characteristic motifs among biological sequences, backtracking the evolutionary paths thro...
Multiple sequence alignment (MSA) may refer to the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. In many cases, the input set of query sequences are assumed to have an evolutionary relationship by which they share a ...
Multiple sequence alignment with the Clustal series of programs:(多序列比对的Clustal系列项目).pdf,Nucleic Acids Research, 2003, Vol. 31, No. 13 3497–3500 DOI: 10.1093/nar/gkg500 Multiple sequence alignment with the Clustal series of programs 1 1 Ramu
Learning to Paraphrase: An Unsupervised Approach Using Multiple-Sequence Alignment Regina Barzilay and Lillian Lee Department of Computer Science Cornell University Ithaca, NY 14853-7501 regina,llee @cs.cornell.edu Abstract We address the text-to-text generation prob- lem of sentence-level paraphrasing...
Our results suggest that HelixFold-Single performs well in predicting flexible regions of these proteins, highlighting its strengths for such applications. HelixFold-Single HelixFold-Single aims to take advantage of both the PLM and the main modules used in AlphaFold2 for single-sequence-based ...
These group-to-group alignment algorithms were applied to multiple sequence alignment with two iterative strategies: a progressive method based on a given binary tree and a randomized grouping--realignment method. The advantages and disadvantages of the four algorithms are discussed on the basis of ...
A standard procedure in many areas of bioinformatics is to use a multiple sequence alignment (MSA) as the basis for various types of homology-based inference. Applications include 3D structure modelling, protein functional annotation, prediction of molecular interactions, etc. These applications, however...
Multiple sequence alignment: Algorithms and applications Elucidation of interrelationships among sequence, structure, function, and evolution (FESS relationships) of a family of genes or gene products is a centra... O Gotoh - 《Advances in Biophysics》 被引量: 221发表: 1999年 ...
A standard procedure in many areas of bioinformatics is to use a single multiple sequence alignment (MSA) as the basis for various types of analysis. However, downstream results may be highly sensitive to the alignment used, and neglecting the uncertaint