Meienberg O, Flammer J and Ludin HP: Subclinical visual field defects in multiple sclerosis. Neurol 227 :125–133, 1982.Mienberg, O, Flammer, J, Ludin, HP (1982) Subclinical visual field defects in multiple scl
Multiple sclerosis (MS) is the most common inflammatory and demyelinating disease of the central nervous system (CNS) and the first cause of nontraumatic and permanent disability in young adults among CNS disorders. Early diagnosis and follow-up are fundamental for optimal disease management, aiming...
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system that results in destruction of both myelin and axons. The cause of the disease is unknown; however, it is believed to be an immune-mediated process. The disease is characterized by relapses and ...
Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system, destroying the myelin and the axon in variable degrees and producing significant physical disability within 20–25 years in more than 30% of patients. The hallmark of MS...
Fisher JB, Jacobs DA, Markowitz CE, Galetta SL, Volpe NJ, Nano-Schiavi MLet al. Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis.Ophthalmology2006;113(2): 324–332. PubMedGoogle Scholar Sepulcre J, Murie-Fernandez M, Salinas-Alaman A, Garcia-Layana ...
Multiple sclerosis (MS) can result in significant mental and physical symptoms, specially muscle weakness, abnormal walking mechanics, balance problems, spasticity, fatigue, cognitive impairment and depression. Patients with MS frequently decrease physical activity due to the fear from worsening the symptom...
Multiple sclerosis (MS) is a chronic neurological condition and the leading cause of non-traumatic disability in young adults. MS pathogenesis leads to the death of oligodendrocytes, demyelination, and progressive central nervous system neurodegeneration
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease, characterised by oligodendrocyte death and demyelination. Oligodendrocyte progenitor cells can differentiate into new replacement oligodendrocytes; however, remyelination is insuff
To some extent, the characteristic imaging appearances of acute disseminated encephalomyelitis differ from those seen in multiple sclerosis, primary progressive inflammatory demyelination and the leucodystrophies. However, as pointed out in Chapter 7, these differences do not in themselves provide a ...
b Initiating Events in Multiple Sclerosis It is not certain whether multiple sclerosis originates from a defect in the immune system or from a defect in the CNS. Data from sequencing the genome of patients with multiple sclerosis suggest that the defect lies in the immune system (109). Various...