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Mitoxantrone (Novantrone) is achemotherapyagent that has been approved by the FDA to treat multiple sclerosis. Treatment with mitoxantrone requires monitoring of cardiac function, and there is a fixed limit to the dose that can be administered to patients. It also carries the long-term risk ofl...
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The present invention concerns treatment of autoimmune diseases with antagonists which bind to B cell surface markers, such as CD19 or CD20.
Multiple sclerosis, progressive disease of the central nervous system involving destruction of the myelin sheath on certain nerve fibers, as a result of which the transmission of nerve impulses becomes impaired, particularly in pathways involving vision,
MS TREATMENT The management of MS involves decreasing signs of disease progression, in addition to treating the day to day symptoms that affect a person’s quality of life. Successful Multiple Sclerosis therapy involves traveling down both of these paths and receiving guidance to do so. The menu...
There is currently no treatment that can address the root causes of multiple sclerosis. In contrast to previous assumptions, moderate sports activity is recommended with nearly all types of MS. When MS patients are affected by spasticity, regular physiotherapy (physical therapy) and/or the use of...
Treating multiple sclerosis costs a great deal for patients and communities. Individually, the nearly 1 million people with MS pay an average annual cost of more than $88,000 for the various treatment options, devices, daily living needs, and insurance needed for their condition. Overall, indirec...
infiltrate[155]. Other studies have shown that the pregnancy hormoneestriolcan ameliorateEAEin mice with an increased production of the Th2 cytokine IL I0 [156], and human studies evaluating the use of estriol as a treatment for multiple sclerosis have initially produced encouraging results [157]...
Cognitive impairment is a common and devastating manifestation of multiple sclerosis (MS). Although disease-modifying therapies have been efficacious for reducing relapse rates in MS, such treatments are ineffective for treating cognitive dysfunction. Alternative treatment approaches for mitigating cognitive pr...