Multiple sclerosis (MS) is a disabling, chronic disease that imposes a significant economic burden on patients and the US healthcare system. The largest cost component for individuals with MS are prescription drugs, specifically disease-modifying therapies (DMTs). Despite an increase in the number ...
Multiple sclerosis (MS), a common cause of neurologic disability in adults, most often begins in the early part of the fourth decade of life. Signs and symptoms are the result of focal destruction of myelin in the CNS. An elevated CSF gamma globulin level or evidence of an oligoclonal CSF...
Compared to large observational studies of MS such as the Sonya Slifka Longitudinal Multiple Sclerosis Study in the US which looked at natural history of MS and The Global Adherence Project (GAP) conducted in twenty-two other countries, TOP MS had comparable proportions of females, a lower propor...
The Natural History of Multiple Sclerosis Studies which have attempted to define the outcome of multiple sclerosis (MS) have methodologic difficulties arising from patient referral biases and the l... B G Weinshenker,G C Ebers - 《Canadian Journal of Neurological Sciences》 被引量: 935发表: 1987...
Treatment-pattern data suggest that some patients with multiple sclerosis (MS) in the Kingdom of Saudi Arabia (KSA) may not be receiving optimal treatment.
Multiple sclerosis is more common in some geographic areas (northern latitudes), and many cases show a stronggenetic predisposition. The cause or trigger of the autoimmune reaction in multiple sclerosis is not known. Viruses have been suspected as triggers (e.g., canine distemper virus), but no...
Our incomplete understanding of the causes and pathways involved in the onset and progression of multiple sclerosis (MS) limits our ability to effectively treat this complex neurological disease. Recent studies explore the role of immune cells at different stages of MS and how they interact with cel...
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Comparative epidemiological studies of multiple sclerosis in South Africa and Japan. J Neurol Neurosurg Psychiatry. 1975 Sep; 38 (9):911–918.Bird AV, Satoyoshi E. Comparative epidemiological studies of multiple sclerosis in South Africa and Japan. J Neurol Neurosurg Psychiatry 1975 September;38(9...
Department of Neurology, School of Medicine, University of California, San Francisco, CA, USAJohn Wiley & Sons, Ltd.Clinical & Experimental NeuroimmunologyNoriko, IsobeJorge R., Oksenberg. (2014) Genetic studies of multiple sclerosis and neuromyelitis optica: Current status in European, African ...