MULTIPLE SCLEROSIS,DEFINITION OF MS,It is defined clinically by the involvement of different parts of the CNS at different times- provided that other disorders causing multifocal central dysfunction have been excluded,EPIDEMIOLOGY,Initial symptoms generally commence before the age of 55 years old with ...
Brainstem syndromes are a common initial presentation of multiple sclerosis. Classic syndromes include internuclear ophthalmoplegia, ataxia, and trigeminal neuralgia. While MRI findings of typical MS lesions in the supratentorial white matter or spinal cord can quickly distinguish demyelinating disease from...
View Media Gallery SeeMultiple Sclerosis, a Critical Images slideshow, for more information on incidence, presentation, and intervention, as well as additional resources. Also, see theAutoimmune Disorders: Making Sense of Nonspecific Symptomsslideshow to help identify several diseases that can cause a v...
Broman T,Anderson O,Bergmann I.Clinical studies on multiple sclerosis: Presentation of an incidence material from Gothenbery. Acta Neurologica Scandinavica . 1981Clinical studies on multiple sclerosis. I. Presentation of an incidence material from Gothenburg. Acta Neurol Scand - Broman, Andersen, et...
Solely psychiatric syndrome may be the first clinical presentation of multiple sclerosis. We report a patient whose first attack was psychotic depression. The present case emphasizes that psychiatric symptoms can occur at any time during the course of the disease and, moreover, may be the ...
To investigate the possibility of local antigen presentation within the central nervous system (CNS) in multiple sclerosis (MS), frozen sections of active chronic MS lesions were stained by the peroxidase-antiperoxidase technique for the demonstration of Ia antigen using a monoclonal antibody. Ia anti...
Unusual Presentation of Spinal Myoclonus After Neuraxial Anesthesia in a Patient With Multiple Sclerosis: A Case Report doi:10.1213/XAA.0000000000001863This case report highlights a unique instance of spinal myoclonus after neuraxial anesthesia. It aims to inform anesthesiology providers, enhancing their ...
Multiple sclerosis (MS) is a complex chronic neuroinflammatory disease characterized by demyelination leading to neuronal dysfunction and neurodegeneration manifested by various neurological impairments. The endocannabinoid system (ECS) is a lipid signal
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. In this study, the Department of Defense Serum Repository (DoDSR), a cohort of over 10 million individuals, was used to generate whole-proteome autoantibody profiles of...
The etiology of the neurogenerative disease multiple sclerosis (MS) is unknown. The leading hypotheses suggest that MS is the result of exposure of genetically susceptible individuals to certain environmental factor(s). Herpesviruses and human endogenous