Disease activity in multiple sclerosis is usually accompanied by blood–brain barrier disruption, which can be assessed with contrast-enhanced magnetic resonance imaging (MRI). This paper describes a technique that gives information about disease activity using magnetization transfer MRI. Image combination ...
Brain MRI without contrast agent is just as effective as the contrast-enhanced approach for monitoring disease progression in patients with multiple sclerosis (MS), according to a new study in the journalRadiology. The findings support the possibility that contrast enhancement can be omitted from rout...
Multiple sclerosis (MS) is a long-lasting (chronic) disease of the central nervous system. It is thought to be an autoimmune disorder, a condition in which the body attacks itself by mistake. MS is an unpredictable disease that affects people differently. Some people with MS may have only m...
Francis GSEvans ACArnold DL Neuroimaging in multiple sclerosis. Neurol Clin. 1995;13147- 171Google Scholar 13. Filippi MHorsfield MATofts PSBarkhof FThompson AJMiller DH Quantitative assessment of MRI lesion load in monitoring the evolution of multiple sclerosis. Brain. 1995;1181601- 1612Google...
Longitudinal MRI in multiple sclerosis: correlation between disability and lesion burden. We followed 18 multiple sclerosis patients clinically and with repeated brain MRIs with and without gadolinium for over 1 year. Clinical evaluations includ... SJ Khoury,CRG Guttmann,EJ Orav,... - 《Neurology》...
NMR imaging of the brain in multiple sclerosis Ten patients with multiple sclerosis (MS) were scanned by means of cranial X-ray computed tomography (CT) with and without intravenous contrast enhancement... IR Young,AS Hall,CA Pallis,... - 《Lancet》 被引量: 129发表: 1981年 Neuroimaging in...
In six patients, the white matter changes were indistinguishable from those seen in multiple sclerosis. Contrast-enhanced CT in two patients showed diffuse meningeal involvement not seen with MRI. MRI is the investigation of choice in ... DH Miller,BE Kendall,S Barter,... - 《Neurology》 被引...
Multiple sclerosis (MS) is a neurodegenerative disorder caused by the immune system mistakenly attacking the myelin sheath, a protective coating around nerve fibers. This results in inflammation, which further damages the myelin sheath, as well as the nerve cells themselves and the cells that ...
In developed countries, multiple sclerosis is the most common neurologic disease that causes progressive neurologic disability in young people. The disease has several different subtypes: relapsing remitting, primary progressive, progressive relapsing, secondary progressive, or benign. The advent of MRI scan...
Our incomplete understanding of the causes and pathways involved in the onset and progression of multiple sclerosis (MS) limits our ability to effectively treat this complex neurological disease. Recent studies explore the role of immune cells at differe