Multiple sclerosis(MS) is an autoimmune chronic inflammatory disease encompassinginflammatory demyelination with axonal transection. According to the Multiple Sclerosis International Federation, as of 2020, there were2.8 millionpeople living with MS worldwide. Further, approximately1 millionpeople in the Unite...
Although the workup for pediatric AACE varies, patients often do not undergo lab testing and imaging, because the overwhelming majority of cases are idiopathic. We describe AACE as the presenting manifestation of multiple sclerosis in a pediatric patient. His only other finding was a horizontal ...
12. A method for treating multiple sclerosis, the method comprising administering to a subject in need thereof, a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a therapeutically effective amount of at least one inhibitor of dipeptidyl peptidase IV, or a stereo...
Multiple sclerosis (MS) is the most common inflammatory and demyelinating disease of the central nervous system (CNS) in Central Europe and North America. Symptoms depend on the localization and severity of MS lesions in the brain and spinal cord and, therefore, vary widely, but typically include...
In this meta-analysis, men with systemic sclerosis had a higher risk of developing cancer than women [9]. However, other studies have not demonstrated an increase in the risk of cancer among scleroderma patients [5, 10, 11]. Multiple myeloma (MM) is a neoplastic plasma-cell disorder that ...
MRIalone cannot be used to diagnose MS; however, it remains theimaging procedure of choicefor confirming MS andmonitoring disease progressionin the brain and spinal cord. According toGrzegorski and colleagues, not all patients with clinically isolated syndrome develop MS. Historically, MScould notbe...
Objective: To determine whether there are differences by sex in the workup of children at high risk for multiple sclerosis (MS).Background: Differences by sex in patterns of investigation have been reported for various autoimmune diseases in adults. We identified children who underwent brain MRI ...
“Better explanations” in multiple sclerosis diagnostic workup: A 3-year longitudinal study. Neurology 2019, 92, e2527–e2537. [Google Scholar] [CrossRef] Dobson, R.; Ramagopalan, S.; Davis, A.; Giovannoni, G. Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically ...