CSF signal-suppressing sequences:Since T2 W sequences are best for demonstrating focal lesions causing increases in cerebral water, lesions in the periventricular brain (e.g.multiple sclerosis) may be obscured by the high signal returned by adjacent CSF. A fluid low-attenuation inversion recovery ...
Cognitive dysfunction is of frequent observation in multiple sclerosis (MS). It is associated with gray matter pathology, brain atrophy, and altered connectivity, and recent evidence showed that acute inflammation can exacerbate mental deficits independently of the primary functional system involved. In ...
Innovative pro-regenerative treatment strategies for progressive multiple sclerosis (PMS), combining neuroprotection and immunomodulation, represent an unmet need. Neural precursor cells (NPCs) transplanted in animal models of multiple sclerosis have shown preclinical efficacy by promoting neuroprotection and re...
Multiple sclerosis, or MS, is a long-term ailment that can influence your optic nerves in your eyed, spinal cord, and the brain I It can cause problems with vision, balance, muscle control, and other basic body functions. The impact is often different for everyone who has the MS. Some ...
Multiple sclerosis (MS) is thought to be an autoimmune disease; however, the exact cause is not known. Early signs and symptoms of MS are fatigue, bladder and bowel problems, vision problems, and numbness, tingling, or pain in certain areas of the body.
Multiple sclerosis (MS) is thought to be an autoimmune disease; however, the exact cause is not known. Early signs and symptoms of MS are fatigue, bladder and bowel problems, vision problems, and numbness, tingling, or pain in certain areas of the body.
Multiple sclerosis (MS) is the most prevalent chronic immune-mediated, inflammatory, and neurodegenerative Central Nervous System (CNS) disease in young adults [1,2]. The pathological hallmark of MS is the presence of focal areas of inflammatory demyelination around post-capillary venules throughout...
Cerebrospinal fluid virological analysis in multiple sclerosis P. FERRANTE AND R. MANCUSO Viral etiology of MS Introduction The detection of virus-specific antibodies, of antigens, and the more recent detec- tion of viral nucleic acids in cerebrospinal fluid (CSF) are powerful tools for the di- ...
MULTIPLE SCLEROSIS Multiple sclerosis (MS) affecting the spinal cord results in the following clinical findings: Lhermitte sign, limb weakness (usually asymmetric spastic paraparasis), andsensory dysfunction.64The presence ofoligoclonal bandsin the CSF will help confirm the diagnosis of MS.65Important...
Mononuclear cells were analyzed in CSF and blood of 102 patients with MS. In CSF, the majority (78%) of cells were T lymphocytes (T3+), and the ratio of inducer (T4+) to suppressor/cytotoxic (T8+) cells was 2:1. No characteristic alterations in CSF phenotypes could be related to ch...