Early symptoms of multiple myeloma frequently mimic rheumatoid diseasedoi:10.1097/00152193-197911000-00002&NANursing2019
Multiple myeloma, also known as Kahler's disease, is a type of blood cancer. There's no cure, but treatments can slow its spread and sometimes make symptoms go away. A type of white blood cell called a plasma cell makes antibodies that fight infections in your body. When you have multi...
Early in the disease, symptoms may be subtle. The symptoms of myeloma generally are nonspecific, meaning they may be caused by many different conditions unrelated to cancer. Any of the following warrant a visit to a health care professional: Unexplained and eventually constant pain, especially in ...
Smoldering myeloma:This is very early in the disease, when there are no symptoms or problems. The blood and kidneys are normal, and there is no bone damage. People who have smoldering myeloma often do not need treatment right away. Stage I:There aren't that many myeloma cells in the body...
The common symptoms always present in multiple myeloma are fatigue and bone pains. The fatigue or a generalised feeling of tiredness is due to the lack of red blood cells which decreases the supply of oxygen to the tissues of the body. Bone pains are because of the loss of calcium from ...
MGUS patients develop multiple myeloma in about two to 19 years after MGUS diagnosis. In addition, smoldering multiple myeloma (also termed inactive) is an early precursor to multiple myeloma. Abnormal proteins in blood or urine are detectable with special testing before multiple myeloma symptoms ...
Fig. 3. The figure illustrates the evolution of multiple myeloma from a premalignant condition (MGUS), through smoldering myeloma, until the development of overt symptomatic disease. Early detection and early intervention in the phase of SMM with preventing or curative strategies may be the way to...
Objective:To evaluate the effect of proteasome inhibitor(bortezomib)on an early multiple myeloma and the influence on the collection of peripheral hematopoietic stem cells.Methods:An adult patient with previously untreated multiple myeloma was treated by bortezomib based regimen including bortezomib,dexamethas...
Usual presentation of multiple myeloma with symptoms like bone pains, renal failure or recurrent infections do not pose much of a diagnostic challenge, but difficulties arise when symptoms are vague and spurious results of laboratory investigations complicate the clinical picture. Hyperphosphatemia is usu...
Introduction: Smoldering multiple myeloma (SMM) is a plasma cell dyscrasia defined by the presence of a monoclonal protein (MP) (≥ 30 g/L in serum or >1g/24-hours in urine) and/or plasma cell bone marrow involvement (BMPC) ≥ 10%, in the absence of symptoms due to the gammopathy....