Ong F, Hermans J, Noordijk EM, Wijermans PW, Kluin-Nelemans JC: Presenting signs and symptoms in multiple myeloma: high percentages of stage III among patients without apparent myeloma-associated ...
Myeloma is the second most common blood cancer, but it is not a common cancer. An estimated 32,110 new patients will be diagnosed with myeloma in the United States in 2019, and men are diagnosed with the condition slightly more frequently than women. The mortality statistic in the U.S. i...
Some signs and symptoms of multiple myeloma include:3,4 Breakdown of the bone resulting in high levels of calcium in the blood (hypercalcemia), which causes dehydration, excessive thirst, nausea, constipation and confusion Poor kidney function Anemia that may result in weakness dizziness and short...
Multiple myeloma, also known as Kahler's disease, is a type of blood cancer. There's no cure, but treatments can slow its spread and sometimes make symptoms go away. A type of white blood cell called a plasma cell makes antibodies that fight infections in your body. When you have multi...
In addition, bone destruction that releases calcium into the circulation may result in calcium deposition in the kidneys and other abnormal sites. Symptoms and signs of multiple myeloma include pain, anemia, weakness, susceptibility to infection, a tendency to hemorrhage, shortness of breath, and ...
Multiple myeloma is cancer that starts in the bone marrow's plasma cells. Symptoms and signs include anemia, skin lesions, weakness, and bone fractures. Read about multiple myeloma prognosis, life expectancy, stages, treatment, diagnosis, and causes.
Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. [1] First described in 1848, MM is part of...
Presenting signs and symptoms of multiple myeloma (MM) include bone pain, pathologic fractures, weakness, anemia, infection (often pneumococcal), hypercalcemia, spinal cord compression, and renal failure. In approximately 30% of cases, MM is discovered through routine blood screening when patients are...
Signs and Symptoms Signs and symptoms of multiple myeloma include bone pain, which may be present in three-fourths of patients. Osteolytic lesions and compression fractures may be seen in the axial skeleton and proximal long bones—the most common being the spine. There is an increased osteoclast...
8. Immunoglobulin E (IgE) Myeloma IgE is the rarest type of multiple myeloma. It causes the same signs and symptoms as other types of multiple myeloma. It tends to be aggressive and progresses to plasma cellleukemiaor spreads outside the bone marrow quickly....