ULTRASOUNDMultipleMYELOMACHESTpainBACKGROUND Chest pain is one of the most common symptoms with which a patient presents to a doctor.Differentials include,but are not limited to,cardiac pulmonary,gastrointestinal,psychosomatic and musculoskeletal causes.In our case,ultrasound of the chest wall paved the ...
Interactions between multiple myeloma (MM) and bone marrow (BM) are well documented to support tumour growth, yet the cellular mechanisms underlying pain in MM are poorly understood. We have used in vivo murine models of MM to show significant induction of nerve growth factor (NGF) by the tum...
What is the treatment and life expectancy of patients with multiple myeloma? What is the most common cause of death? A number of different treatment options have been developed for patients with MM. This includes hematopoietic stem-cell transplant (HSCT), chemotherapy, immunomodulatory therapy,monoclo...
Normally, plasma cells form part of theimmune system. They produce immunoglobulins (antibodies) which help fight infection. In multiple myeloma, abnormal plasma cells in the bone marrow multiply too fast. They take up too much space in the bone marrow and prevent the normal production of other ...
Presenting signs and symptoms of multiple myeloma (MM) include bone pain, pathologic fractures, weakness, anemia, infection (often pneumococcal), hypercalcemia, spinal cord compression, and renal failure. In approximately 30% of cases, MM is discovered through routine blood screening when patients are...
Being male:It's slightly more common in men. Being overweight Heredity:Other people in your family have had multiple myeloma. History:You've had another plasma cell disease. Symptoms In the early stages of multiple myeloma, you might not have symptoms, or they might be very mild. Everyone ...
Many times a multiple myeloma may not have any symptoms and is detected on routine blood tests for some other reason. This stage is called smouldering multiple myeloma. Treatment at this stage gives the most favourable results due to the relatively decreased number of cancerous cells. Even ...
Myeloma is the second most common blood cancer, but it is not a common cancer. An estimated 32,110 new patients will be diagnosed with myeloma in the United States in 2019, and men are diagnosed with the condition slightly more frequently than women. The mortality statistic in the U.S. ...
Multiple myeloma is a type of cancer, or more precisely, it is a cancer of plasma cells. These cells are a type of white blood cells, they can be found in the bone marrow and they are in charge of making antibodies that are necessary in fighting various infections. The reason why this...
The treatment of multiple myeloma presents a variety of unique challenges due to the complex molecular pathophysiology and incurable status of the disease at this time. Given that MM is the second most common blood cancer with a characteristic and unavoidable relapse/refractory state during the ...