Multiple myeloma (MM) is rapidly emerging as a new model of human neoplastic disease, after decades of limited interest by laboratory investigators in part because of its relatively low incidence and often indolent clinical course. Novel concepts in therapy, including effective salvage therapy with ...
Multiple Myeloma Multiplemyelomais amalignancyof plasma cells, which are derived fromB lymphocytes(B cells) and are responsible for creating antibodies. The disease is characterized by infiltration of themyeloma cellsinto the bone and, eventually, other organs. These malignant cells produce monoclonal (...
Role of CAR-T Therapy in R/R Multiple Myeloma Binod Dhakal, MD, MS March 19th 2024 Binod Dhakal, MD, explores the role of CAR-T cell therapy in R/R MM, including an overview of the process, patient selection criteria, and identifying suitable candidates. ...
Disease overview: Multiple myeloma accounts for 10% of all hematologic malignancies.doi:10.1002/ajh.22237TefferiAyalewRajkumarS.VincentAmerican Journal of HematologyS. Vincent Rajkumar. (2012) Multiple myeloma: 2012 update on diagnosis, risk-stratification, and management. American Journal of Hematology ...
The meaning of MULTIPLE MYELOMA is a disease of bone marrow that is characterized by the presence of numerous myelomas in various bones of the body.
Multiple Myeloma Bone Disease - ScienceDirectEvangelos TerposMaria GavriatopoulouEncyclopedia of Endocrine Diseases (Second Edition)
Osteonecrosis of the jaw complicating bisphosphonate treatment for bone disease in multiple myeloma: an overview with recommendations for prevention and tr... Background: CD26, a 110-kDa transmembrane glycoprotein with DPPIV activity, has been implicated in tumorigenesis and shown to be expressed in ...
Cancer cells are well-known for their capacity to adapt their metabolism to their increasing energy demands which is necessary for tumor progression. This is no different for Multiple Myeloma (MM), a hematological cancer which develops in the bone marrow
In January 2015, Edward started chemotherapy treatment. After three cycles of chemotherapy, the progression of his myeloma was slowed. Six months later Edward had a stem cell transplant, but it did not eliminate the disease. In July 2016, the disease relapsed and Edward received additional round...
This case series assesses whether environmental exposures from the World Trade Center disaster site are associated with multiple myeloma and its precursor