Different blood, urine, and bone marrow tests help diagnose multiple myeloma, and determine treatment. WebMD explains what you can expect from each from each type of test and what to expect next.
Multiple Myeloma Diagnosis Your doctor may suspect multiple myeloma if you have a blood test for something else and it shows: Too much calcium in your blood (hypercalcemia) Too few red blood cells (anemia) Kidney problems High total protein levels in your blood, but low levels of one called...
Multiple Myeloma: Using Absolute Lymphocyte Count to Predict Outcomes After CAR T-Cell Therapy A simple blood test that measures lymphocyte counts may predict whether patients with relapsed multiple myeloma are going to respond well to chimeric antigen receptor (CAR) T-cell immunotherapy, according to...
Peripheral blood biomarkers of tumor microenvironment and immune surveillance are independent prognostic factors in multiple myeloma. The timing and prognostic impact of immune reconstitution has been studied after autologous hematopoietic stem cell transplantation, less is known about its significance in newly...
Although multiple myeloma (MM) is still considered as an incurable disease by current standards, the development of several combination therapies, and immunotherapy approaches has raised the hope towards transforming MM into an indolent, chronic disease,
In the MASTER study (NCT03224507), daratumumab+carfilzomib/lenalidomide/dexamethasone (D-KRd) demonstrated promising efficacy in transplant-eligible newly diagnosed multiple myeloma (NDMM). In GRIFFIN (NCT02874742), daratumumab+lenalidomide/bortezomib/dexamethasone (D-RVd) improved outcomes for transplant-eli...
Presenting signs and symptoms of multiple myeloma (MM) include bone pain, pathologic fractures, weakness, anemia, infection (often pneumococcal), hypercalcemia, spinal cord compression, and acute kidney injury. In approximately 30% of cases, MM is discovered through routine blood screening when patient...
外科学教学课件:Multiple Myeloma MultipleMyeloma MM 浆细胞病(plasmacelldyscrasia)是指浆细胞或产生免疫球蛋白的B淋巴过度增殖所引起的一组疾病,血清或尿中出现过量的单克隆免疫球蛋白或其轻链或重链片段为其特征的一组疾病。浆细胞病在临床上可分为两类:一类为具有明显临床症状和病理特征的恶性浆细胞病。另...
Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. [1] MM is part of a spectrum of diseases ...
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