In this issue of Leukemia and Lymphoma, Chari and colleagues expand the armamentarium for the treatment of multiple myeloma to include the Bruton tyro-sine kinase inhibitor (BTK) ibrutinib. In this phase-1 trial, ibrutinib at a dose of 840 mg (twice the dose used for chronic lymphatic ...
Latest News Roundtable Roundup: Choosing a Bispecific Antibody for R/R Multiple Myeloma ByTargeted Oncology Staff December 23rd 2024 In separate, live events, Binod Dhakal, MD, MS; and Laahn H. Foster, MD, polled oncologists on therapeutic options for a patient with multiple myeloma and progr...
Cancer researchDrug discovery and developmentNanomedicineNews Novel therapeutic delivered to the multiple myeloma tumor microenvironment in the bone marrow inhibits key pathway in the metastasis of the disease. A recent research effort from theUniversity of Pennsylvania(PA, USA) has developed a promising ...
multiple myeloma cure; plasma cell disease Abstract A 52-year-old man with a plasmacytoma of the body of T-10 in February 1965 returned 6 months later with multiple myeloma characterized by bone pain, osteolytic lesions, and IgD λ monoclonal protein in the serum, 6.1 g of Bence Jones prot...
“I tell myfellowsthat my goal is not to cure myeloma. It’s to give my patients the longest life, with the best quality of life, with the least amount of treatment necessary. That goal is met by achieving the deepest response—by getting to a complete remission. The use of optimal in...
Moving Mountains 4 Multiple Myeloma is an award-winning collaboration between the Multiple Myeloma Research Foundation (MMRF) and CURE to raise research funds, awareness and hope for myeloma patients. Patients, caregivers, myeloma doctors and nurses and myeloma loved ones take on challenging mountains ...
I would love to see a cure for multiple myeloma. The disease is very resistant to drugs, and the recurrence rate is high. If we could get to a point where we stop it completely, that would be remarkable. And, of course, if any of the therapies that we discover or develop might play...
Likewise, in trying to find a cure for myeloma, we need to look at different research projects in parallel and get the best advice possible to come up with likely projects. Q: Why is this the right time for the Black Swan Research Initiative? A: With novel therapies, we see long-te...
Despite significant advances in the treatment of multiple myeloma which had led to unprecedented rates of response and survival, patients still relapse, and cure remains elusive. We propose in this review a roadmap to achieve the dream of cure for multiple myeloma based on five complementary strate...
Pomalyst is a prescription medication used to treat multiple myeloma and Kaposi sarcoma (KS). Serious side effects include birth defects and miscarriage when taken in pregnancy, venous and arterial thromboembolism, low white blood cells (neutropenia), lo