I’m a Clinician. Discover the advantages of EasyM™ mass spectrometry-based blood test for MRD monitoring in multiple myeloma
In some cases of myeloma, excess protein in the blood can cause a condition called hyperviscosity syndrome. The type and amount of immunoglobulin protein can result in thickening the blood beyond normal blood viscosity, which may result in alteration in a variety of bodily, including mental, proc...
Background: This study aimed to investigate the value of the peripheral blood neutrophil-to-lymphocyte ratio (NLR) and lymphocyte-to-monocyte ratio (LMR) in the prognosis of patients with multiple myeloma (MM). Methods: Before treatment, the NLR and LMR and all clinical ...
Effect of lenalidomide therapy on mobilization of peripheral blood stem cells in previously untreated multiple myeloma patients. Autologous stem cell transplantation (ASCT) improves survival in patients with previously untreated multiple myeloma (MM) and relapsed, chemotherapy-sensit... Mazumder,Kaufman,Nies...
Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. [1] First described in 1848, MM is part of...
multiplemyeloma ; changesofbloodlipid ; clinicalstage ; chemotherapy 低蛋白血症见于多种恶性肿瘤,而血脂水平 与多种恶性肿瘤存在相关性 [ 1-2 ] 。多发性骨髓 瘤( MM )是一种主要发生在中老年人群的浆细胞 恶性增殖性疾病,约占血液肿瘤的 10% [ 3 ] 。 Pui 等 [ 4 ] 研究表明,血液系统的恶性肿瘤至...
Medicine and section chief of hematology at Perlmutter Cancer Center, said in a press release. “Her work has been fundamental to revealing the importance of achieving complete remission inmyeloma therapy, and under her leadership, the center is poised to extend treatment adv...
Presenting signs and symptoms of multiple myeloma (MM) include bone pain, pathologic fractures, weakness, anemia, infection (often pneumococcal), hypercalcemia, spinal cord compression, and renal failure. In approximately 30% of cases, MM is discovered through routine blood screening when patients are...
Myeloma cells spread through the bone marrow. They can damage your bones and crowd out healthy blood cells. These cells also make antibodies that can't fight off infections. This cancer is often called multiple myeloma because it's found in many parts of your bone marrow. ...
In the MASTER study (NCT03224507), daratumumab+carfilzomib/lenalidomide/dexamethasone (D-KRd) demonstrated promising efficacy in transplant-eligible newly diagnosed multiple myeloma (NDMM). In GRIFFIN (NCT02874742), daratumumab+lenalidomide/bortezomib/de