Multiple myeloma, also known as Kahler's disease, is a type of blood cancer. There's no cure, but treatments can slow its spread and sometimes make symptoms go away. A type of white blood cell called a plasma cell makes antibodies that fight infections in your body. When you have multi...
Multiple myeloma is a type ofcancerof the plasma cells (a type of white blood cells) of the bone marrow. Plasma cells are protein-making cells that normally produce the different kinds of antibodies of the disease-fighting immune system. In multiple myeloma, the plasma cells undergo a malignan...
Conclusions Multiple myeloma is a blood cancer showing a very high recurrence rate even after treatment, so a new diagnostic system replacing BM biopsy is absolutely necessary for patient's convenience. Although various methods have been attempted to identify MM cells in the PB, but it was ...
Check point signaling is an important immunosuppressive component of the myeloma microenvironment [128]. Induction of check point expression on B cells due to the effective T cell activation conferred by BsAb is a well-studied phenomenon [129,130]. Due to the release of the pro-inflammatory cytok...
myeloma cell that sticks out as a spike, years before it becomes cancer. This so-called "monoclonal spike" is found in about 3 percent of people over 50 years old, according to Reu. But that finding on a blood test does not mean a person will develop multiple myeloma; he estimates ...
Plasma cells are a type of white blood cell that makes antibodies. Myeloma cells spread through the bone marrow. They can damage your bones and crowd out healthy blood cells. These cells also make antibodies that can't fight off infections. This cancer is often called multiple myeloma because...
Multiple myeloma (MM) is a post-Germinal Center cancer characterized by a multifocal proliferation of clonal, long-lived plasma cells (PCs) within the bone marrow (BM)1. This multistep malignancy is preceded by an age-progressive premalignant condition called monoclonal gammopathy of undetermined sig...
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Multiple Myeloma By Julia Cipriano, MS / September 2024 Delays in Oral Antimyeloma Treatment Initiation: Role of Social Determinants of Health A retrospective cohort study published in Blood Cancer Journal by Gasoyan et al revealed discrepancies between the timing of the initiation of any treatment...
As the prognosis for multiple myeloma (MM) has significantly improved and patients remain on therapy longer, there is a need for supportive care interventions to optimize patient quality of life (QOL) and functional status over the course of cancer treatment. MM is characterized by a significant ...