biopsyMultiple myeloma is a malignant disease that results in the proliferation of a single plasma cell clone. The clinical manifestations are anemia, bone pain, bone fractures, hypercalcemia, hypergammaglobulinemia, increased erythrocyte sedimentation rate, rouleaux formation on the peripheral blood smear...
Myeloma Summary Multiple myeloma is a monoclonal gammopathy characterized by bone marrow infiltration by plasma cells or a biopsy-proven plasmacytoma, monoclonal p... J. San Miguel,P. Rodríguez‐Otero,E. M. Ocio,... - John Wiley & Sons, Ltd 被引量: 9发表: 0年 Expert panel consensus stat...
multiple myeloma (SMM). These phenotypes lack myeloma-defining events (MDE), such as end-organ damage or amyloidosis. However, patients affected have an abnormally higher rate of monoclonal B cells in their bone marrow (MGUS, SMM) or elevated serum and urinary monoclonal protein that is a clas...
Tests of the blood (such as serum protein electrophoresis and the serum free light chain assay), and urine (urine protein electrophoresis) can detect M proteins produced by myeloma cells. A bone marrow biopsy, typically obtained from the hip, is recommended for all patients in whom multiple mye...
The third known case of IgE multiple myeloma is described. The patient was a 65-yr-old woman who died 11 mo after a diagnosis of multiple myeloma was made by a surgical biopsy of the left iliac crest. Her serum contained approximately 2.7 g/100 ml of a paraprotein of mid-γ mobility....
Other names for multiple myeloma: kahler disease, plasma cell myeloma, myeloma, myelomatosis, MM About Smart Patients Smart Patients is an online community for patients and families affected by a variety of illnesses. Here you can learn at your own level about scientific developments related to...
More Tests for Multiple Myeloma Diagnosis Bone Marrow Examination Examination of the bone marrow is necessary to make the diagnosis of myeloma and to estimate the extent of the disease. Abone marrow aspirationand biopsy is the procedure to collect a sample of bone marrow. ...
Multiple Myeloma Multiplemyelomais a multifocal malignant proliferation of monoclonal plasma cells that occurs most commonly in men older than 60 years. Diagnosis is confirmed by bone biopsy or by demonstratingBence Jones proteins(free light chains) in urine ormonoclonal gammopathyin serum. Although it...
Multiple myeloma, also known as Kahler's disease, is a type of blood cancer. There's no cure, but treatments can slow its spread and sometimes make symptoms go away. A type of white blood cell called a plasma cell makes antibodies that fight infections in your body. When you have multi...
Multiple myeloma (MM) remains incurable and its diagnosis relies heavily on bone marrow aspiration and biopsy. CD38 is a glycoprotein highly specific for MM. Antibody therapeutics (e.g., daratumumab) targeting CD38 have shown encouraging efficacy in treating MM, either as a monotherapy agent or in...