Multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) are closely related B-cell cancers. Parallel and divergent features of these diseases are reviewed. In MM, expression of multiple hemopoietic lineage-associated antigens on the malignant cells and the substantial likelihood of progression to...
Myeloma cells spread through the bone marrow. They can damage your bones and crowd out healthy blood cells. These cells also make antibodies that can't fight off infections. This cancer is often called multiple myeloma because it's found in many parts of your bone marrow. Men over age 50 ...
Significantly increased risks of leukemia associated with exposure to high acute doses of ionizing radiation are well-studied and recognized (UNSCEAR, 2008). The evidence of radiation-associated risks of other hematologic cancers, including Hodgkin lymphoma (HL), multiple myeloma (MM) and non-Hodgkin...
In the past decade, many progresses have been made in our knowledge of the genetics of multiple myeloma. The use of molecular cytogenetic techniques has led to the identification of several recurrent (cyto)genetic abnormalities, representing either progn
AbstractUranium workers are chronically exposed to low levels of radon decay products (RDP) and gamma (纬) radiation. Risks of leukemia from acute and high doses of 纬-radiation are well-characterized, but risks from lower doses and dose-rates and from RDP exposures are controversial. Few stu...
Past history of chronic infectious, autoimmune, allergic, and musculoskeletal disorders was abstracted from medical records for leukemia (n = 299), non-Hodgkin's lymphoma (NHL, n = 100), and multiple myeloma (n = 175) cases and matched controls (n = 787). Little difference was found ...
AbstractHairy cell leukemia (HCL) and multiple myeloma (MM) originate from mature B-cell and they are characterized by different clinical symptoms and treatment. Their clinical outcome is also different. The introduction of 2-CdA makes HCL a potentially curable disease, but MM still remains incurab...
Multiple myeloma (MM) is a debilitating malignancy that is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance (MGUS) to plasma cell leukemia. First described in 1848, MM is characterized by a proliferation of malign
Multiple myeloma (MM) is the second most common blood malignancy. Epidemiological family studies going back to the 1920s have provided evidence for familial aggregation, suggesting a subset of cases have an inherited genetic background. Recently, studies
Leukemia, lymphoma and multiple myeloma mortality (1950–1999)and incidence (1969–1999) in the Eldorado uranium workers cohortLydia B. Zablotskaa,n, Rachel S.D. Laneb, Stanley E. Frostc, Patsy A. ThompsonbaDepartment of Epidemiology and Biostatistics, School of Medicine, University of Califor...