Ignoring censoring issue in any analysis may lead to the biased results. For a regression analysis where multiple censored biomarkers are included as predictors, we develop multiple imputation methods based on Gibbs sampling approach. The simulation study shows that our method ...
1 Quantile-Quantile plot of total CM meta-analysis. Quantile-quantile plots of negative log10 two-sided P value derived from a fixed-effects inverse-variance weighted meta-analysis of log(OR) effect-sizes derived from the logistic regression GWAS listed in Supplementary Table 1. All confirmed ...
Multilevel models often include nonlinear effects, such as random slopes or interaction effects. The estimation of these models can be difficult when the u
Urinary proteomics is emerging as a potent tool for detecting sensitive and non-invasive biomarkers. At present, the comparability of urinary proteomics data across diverse liquid chromatography−mass spectrometry (LC-MS) platforms remains an area that
FromAustin Nichols <austinnichols@gmail.com> Tostatalist@hsphsun2.harvard.edu SubjectRe: st: Combining multiple imputation with propensity score matching DateTue, 2 Mar 2010 12:10:29 -0500 References: st: Combining multiple imputation with propensity score matching ...
In cases of missing pixels, we used the multiple imputation by chained equation method84 for data imputation using nearest observations. We included the original BI,85 which estimates how the average abundance of native terrestrial species in a region compares with their abundances before extensive ...
To understand the potential of methylation as a predictive biomarker of severity with clinical utility, we compared the accuracy of three models in classifying binary disease severity in our cohort using elastic net regression. Elastic net regression is a form of penalised regression that is useful ...
Although a large amount of research has been devoted to estimation and inference for... PW Bernhardt,HJ Wang,D Zhang - 《Statistics in Biosciences》 被引量: 8发表: 2015年 Survival analysis with time-dependent covariates subject to missing data or measurement error: Multiple Imputation for Joint...
We examined the relationship between genotype and MM in each GWAS, assuming a log-additive model72. Meta-analysis under a fixed-effects inverse-variance weighted model was performed using META v1.773. Variants in the meta-analysis only included those with an imputation quality score (info) > 0.8...
were also excluded. Multidimensional scaling was performed using HapMap3 reference data. Samples from individuals of non-European ancestry and ethnic outliers with >3 standard deviation difference from the European samples were identified and further removed (finalNat this stage = 158). Imputation was...