Diseases prediction has been performed by machine learning approaches with various biological data. One of the representative data is the gut microbial community, which interacts with the host’s immune system. The abundance of a few microorganisms has b
The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly. Lancet Microbe 3, e969–e983 (2022). Article CAS PubMed Google Scholar Ward, T. L., Knights, D. & Gale, C. A. Infant fungal communities: current knowledge and ...
Despite improvements in outcome, 15-25% of newly diagnosed multiple myeloma (MM) patients have treatment resistant high-risk (HR) disease with a poor survival. The lack of a genetic basis for HR has focused attention on the role played by epigeneti
Multiple myeloma (MM) is a treatable plasma cell cancer with no cure. Clinical evidence shows that the status of minimal residual disease (MRD) after treatment is an independent prognostic factor of MM. MRD indicates the depth of post-therapeutic remissi
human gene, and variants in highly damaged genes are less likely to be disease-causing. We observed a high weight assigned to the GDI feature, indicating that genes with a lower GDI tended to have higher MAGPIE prediction scores and were more likely to be pathogenic (Additional file2: Fig....
Ra-gcn: Graph convolutional network for disease prediction problems with imbalanced data Medical Image Analysis [J], 75 (2022) Google Scholar Grattarola et al., 2021 GRATTAROLA D, LIVI L, ALIPPI C, et al. 2021. Seizure localisation with attention-based graph neural networks. bioRxiv [J]: ...
Baseline observation carried forward PROCAS: Predicting of Cancer at Screening BCPP: Breast cancer prevention programme MDPP: Multiple disease prevention programme References Evans DG, Astley S, Stavrinos P, Harkness E, Donnelly LS, Dawe S, et al. Improvement in risk prediction, early detecti...
Citrus is one of the most valuable fruits worldwide and an economic pillar industry in southern China. Nevertheless, it frequently suffers from undesirable environmental stresses during the growth cycle, which severely restricts the growth, development a
AlphaFold2 (ref.1) has revolutionized structural biology by accurately predicting single structures of proteins. However, a protein’s biological function often depends on multiple conformational substates2, and disease-causing point mutations often cause population changes within these substates3,4. We ...
Among these, MRI is a non-invasive imaging technique commonly used for disease diagnosis owing to its high spatial resolution with no depth limit [2,3]. Currently, various Gd-chelates are commercially available as MRI contrast agents. In addition, recent studies have demonstrated that Gd-based ...