Proteus syndrome is a complex and highly variable disorder comprising malformations and overgrowth of multiple tissues. We present a 65-year-old Japanese man who had multiple spinal meningiomas and accompanying neural symptoms. His right leg showed hypertrophy with cerebriform connective-tissue naevus on...
Neurodegeneration in Multiple Sclerosis: Symptoms of Silent Progression, Biomarkers and Neuroprotective Therapy—Kynurenines Are Important Players by Dániel Sandi 1, Zsanett Fricska-Nagy 1, Krisztina Bencsik 1 and László Vécsei 1,2,3,* 1 Albert Szent-Györgyi Clinical Centre, Department ...
This impairs nerve signaling and causes a wide variety of potential symptoms, such as muscle weakness, pain, and problems with thinking and memory. The precise cause of MS is unknown. Understanding MS The Different Types of MS Multiple Sclerosis Facts and Statistics What Are the Stages of ...
Fatty and connective tissue infiltration of the thighs in both cases corresponded to a posterior-dominant distribution [36, 37], with the key aspect being the symmetrical, fibrosing nature of the change in the semitendinosus, which limits hip flexion. In our patient, there were no signs of ...
Primary progressive multiple sclerosis(PPMS):is the rarest course of multiple sclerosis, only approximately 15% of multiple sclerosis patients havePPMS. It is characterized by a slowly worsening of the neurological function from the onset of symptoms. This course of multiple sclerosis may be confused...
Loneliness—the subjective experience of social disconnection—is now widely regarded as a health risk factor. However, whether the associations between loneliness and multiple diseases are consistent with causal effects remains largely unexplored. Here
Cowden disease, also termed Cowden syndrome and multiple hamartoma syndrome, is an autosomal dominant condition with variable expression that can be associated with a mutation in the PTEN gene on arm 10q, as reported by Liaw et al. [1] Signs and symptoms Also see Presentation. Cowden disease...
(N = 44), neurodegenerative disorder (N = 33), psychosis (N = 29), and one each of anorexia nervosa, epilepsy, and cancer. Paraffin sections from the rostral pons, frontal motor cortex, hippocampus (including the lateral geniculate nucleus), midbrain and cerebellar dentate ...
Connective tissue disorders associated with primary acquired UH include lathyrism, Marfan syndrome, Loeys–Dietz syndrome, and Ehlers–Danlos syndrome. Lathyrism is an acquired connective tissue disorder that inhibits collagen cross-linking when people eat a diet high in grass peas, whereas Marfan ...
Different types of biomarkers in multiple sclerosis:Diagnostic biomarkersare used to confirm the diagnosis of MS. A test used to diagnose a disease often measures a type of biomarker called a “surrogate.” Diagnostic biomarkers may facilitate earlier detection of a disorder than can be achieved by...