Proteus syndrome is a complex and highly variable disorder comprising malformations and overgrowth of multiple tissues. We present a 65-year-old Japanese man who had multiple spinal meningiomas and accompanying neural symptoms. His right leg showed hypertrophy with cerebriform connective-tissue naevus on...
Osteogenesis imperfecta (OI) is an inherited connective tissue disorder characterized by small stature, reduced bone mineral density, and frequent fractures (85). More than 85% of patients with OI fall into four (types I–IV OI) of nine potential subtypes, due to predominantly dominant mutat...
Fatty and connective tissue infiltration of the thighs in both cases corresponded to a posterior-dominant distribution [36, 37], with the key aspect being the symmetrical, fibrosing nature of the change in the semitendinosus, which limits hip flexion. In our patient, there were no signs of ...
Primary progressive multiple sclerosis(PPMS):is the rarest course of multiple sclerosis, only approximately 15% of multiple sclerosis patients havePPMS. It is characterized by a slowly worsening of the neurological function from the onset of symptoms. This course of multiple sclerosis may be confused...
Neurodegeneration in Multiple Sclerosis: Symptoms of Silent Progression, Biomarkers and Neuroprotective Therapy—Kynurenines Are Important Players by Dániel Sandi 1, Zsanett Fricska-Nagy 1, Krisztina Bencsik 1 and László Vécsei 1,2,3,* 1 Albert Szent-Györgyi Clinical Centre, Department ...
This impairs nerve signaling and causes a wide variety of potential symptoms, such as muscle weakness, pain, and problems with thinking and memory. The precise cause of MS is unknown. Understanding MS The Different Types of MS Multiple Sclerosis Facts and Statistics What Are the Stages of ...
Loneliness—the subjective experience of social disconnection—is now widely regarded as a health risk factor. However, whether the associations between loneliness and multiple diseases are consistent with causal effects remains largely unexplored. Here
RESULTS: All three patients had neurological symptoms... J Oksi,H Kalimo,RJ Marttila,... - 《J Neurol Neurosurg Psychiatry》 被引量: 83发表: 1998年 Multiple intracranial aneurysms in a patient with autosomal recessive polycystic kidney disease. Autosomal recessive polycystic kidney disease (ARPKD)...
Apart from some diseases that are already prevalent in the general population such as diseases of the circulatory system, the primary comorbidities for patients with MSA relate mainly to the autonomic disorder, instead of the MSA-associated motor symptoms. This emphasizes that effective management of ...
lymphoid tissue inducer (LTi) cells. These cells are known to promote the development of lymph nodes and related tissues during fetal life, but their role during adulthood has been unclear. The new study marks the first time that LTi cells have been implica...