Multi-cohort study identifies social determinants of systemic inflammation over the life courseChronic inflammation has been proposed as having a prominent role in the construction of social inequalities in health. Disentangling the effects of early life and adulthood social disadvantage on inflammation is...
a study of ageing in an elderly English population, was the cohort with the lowest prevalence of normal BMI, and with the highest proportion of obese individuals compared to the other cohorts. These results highlight the important to take into account the social distribution of risk factors in ...
SHORT COMMUNICATION British Journal of Cancer (2016) 114, 813–818 | doi: 10.1038/bjc.2016.9 Keywords: Breast cancer; colorectal cancer; lung cancer; prostate cancer; working hours Long working hours and cancer risk: a multi-cohort study Katriina Heikkila*,1,2, Solja T Nyberg2, Ida EH ...
This was a multinational, multi-cohort study of patients with T2D in five data sources: the Danish National Health Registers (DNHR) (Denmark), PHARMO Data Network (The Netherlands), Valencia Health System Integrated Database (VID) (Spain), Japan Chronic Kidney Disease Database Extension (J-CK...
This retrospective, multicohort study included three datasets. The development dataset, consisting of preoperative and early NAC DCE-MRI data from 255 patients, was used to create an imaging signature-based multitask model for predicting tumor shrinkage patterns and pathological complete response (pCR)...
Methods: In this exploratory multicohort study of 283,414 community-dwelling participants, we examined 22 common hospital-treated physical diseases as risk factors for dementia. Results: During a median follow-up of 19 years, a total of 3416 participants developed dementia. Those who had erysipelas...
Our study suggests different educational patterning of inflammatory biomarkers. Further large-scale research is needed to explore social differences in the inflammatory cascade in greater detail and the extent to which these differences contribute to social inequalities in health.Previous...
This study determined the association between respiratory symptoms and death from respiratory causes over a period of 45 years. In four cohorts of random samples of Norwegian populations with 10
(bilirubin and platelet count) were performed to identify factors independently associated with risk of developing adverse events or safety events (eg, drug discontinuation, alanine aminotransferase (ALT) elevation, hepatic decompensation/death).A total of 1096 patients contributed data to the study. Fos...
Self-reported cognitive decline is an early behavioral manifestation of Alzheimer disease (AD) at the preclinical stage, often believed to precede concerns reported by a study partner. Previous work shows cross-sectional associations with β-amyloid (Aβ) status and self-reported and study partner-...