The affinity of a lectin from the sponge Geodia cydonium (GCL-I) for multi-antennary Galβ1→4GlcNAc and Galβ1→3GalNAc ligands was studied by both the biotin/avidin-based microtiter plate lectin binding assay and the inhibition of lectin-glycoform interaction. Among the glycoforms tested ...
et al. Autoimmune hepatitis displays distinctively high multi-antennary sialylation on plasma N-glycans compared to other liver diseases. J Transl Med 22, 456 (2024). https://doi.org/10.1186/s12967-024-05173-z Download citation Received03 November 2023 Accepted05 April 2024 Published14 May 2024...
multi-antennary gall1c4glcnac and gall1c3galnac clusters as important ligands for a lectin isolated from the sponge geodia cydonium JH Wu,SC Song,YY Chen,... 被引量: 0发表: 2019年 Carbohydrate structures of nonspecific cross-reacting antigen-2, a glycoprotein purified from meconium as an ...
In the group B antigen all the oligosaccharides are linked by one type of phosphodiester bond from O6 of the D-glucitol residue of one oligosaccharide to O6 of the alpha-D-galactopyranosyl residue of the next to form a complex and highly branched multiantennary structure. However, despite the...
A modular set of oligosaccharide building blocks was developed for the synthesis of multiantennary N-glycans of the complex type, which are commonly found on glycoproteins. The donor building blocks were laid out for the elongation of a core trisaccharide acceptor (-mannosyl chitobiose) ...
Canales, A., Mallagaray, A., Perez-Castells, J., Boos, I., Unverzagt, C., Andre, S., Gabius, H.J., Canada, F.J., Jimenez-Barbero, J.: Breaking pseudo-symmetry in multiantennary complex N-glycans using lanthanide-binding tags and NMR pseudo-contact shifts. Angew Chem Int Ed ...
This integrated strategy permits for the first time the use of a single approach for multiantennary N-glycans as well as their bisected derivatives via imidates, with unprecedented yields even in a one-pot double glycosylation. With this new method, rare N-glycans of the bisected type can ...
Thomas A, Shukla A, Sivakumar S, Verma S. Assembly, postsynthetic modification and hepatocyte targeting by multiantennary, galactosylated soft structures. Chem Commun 2014;50(99):15752- 15755.Thomas, A.; Shukla, A.; Sivakumar, S.; Verma, S. Assembly, Postsynthetic Modification and Hepatocyte ...
Recently, by means of paramagnetic NMR spectroscopy the analysis of branch-selective interaction of multiantennary N-glycans with lectins was accomplished. [2,3]T. KaragiannisM. MonnichL. Perkams29th International Carbohydrate Symposium (ICS 2018): Book of Abstracts : Lisbon, Portugal, 14-19 ...
Thomas, A.; Shukla, A.; Sivakumar, S.; Verma, S. Assembly, Postsynthetic Modification and Hepatocyte Targeting by Multi- antennary, Galactosylated Soft Structures. Chem. Commun. 2014, 50, 15752-15755.Thomas A, Shukla A, Sivakumar S, Verma S. Assembly, postsynthetic modification and ...