Brooks DJ, Ibanez V, Sawle GV, Quinn N, Lees AJ, Mathias CJ et al (1990) Differing patterns of striatal18F-dopa uptake in Parkinson’s disease, multiple system atrophy, and progressive supranuclear palsy. Annals Neurology 28 (4):547–555. https://doi.org/10.1002/ana.410280412 Article Goog...
et al. Increased brain histamine levels in Parkinson’s disease but not in multiple system atrophy. J. Neurochem. 81, 954–960 (2002). Article CAS PubMed Google Scholar Braak, H. et al. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol. Aging 24, 197–211 ...
However, existing systematic approaches assume that, for a drug to treat a disease, the proteins targeted by the drug need to becloseto or even need tocoincidewith the disease-perturbed proteins10,11,12,13,14(Fig.1). As such, current approaches fail to capture biological functions, through ...
Multiclass classification Relevance vector machine FDG PET Parkinson's disease Multiple system atrophy Progressive supranuclear palsy Corticobasal syndrome 1. Introduction Computer-aided diagnosis (CAD) integrates data processing, mathematics and statistics into computerized techniques to maximize the information ...
suggesting an evident inhibition of IAV replication. These results were also confirmed by in vivo experiments since its intranasal administration to WSN-infected Balb/c mice (0.3 mg/kg/day) showed a reduction of symptoms severity, including pulmonary lesions, inflammation, and atrophy of the thymus...
By combining multiple types of features, they aimed to improve the accuracy of disease detection. Kim et al. [58] developed a multimodal and integrative decision support system for predicting postoperative cardiac events in multiple surgical cohorts. They incorporated multimodal features derived from ...
Background:Kidney allograft failure is a common cause of end-stage renal disease. We aimed to develop a dynamic artificial intelligence approach to enhance risk stratification for kidney transplant recipients by generating continuously refined predictions of survival using updates of clinical data. Methods...
In the production of pigs, weaning stressors include nutrition, psychology, and environment, leading to villous atrophy, crypt hyperplasia [8], and the production of excessive free radicals. Consequently, the induced intestinal barrier increases membrane permeability, which is conducive to the invasion...
SCI; cardiometabolic disease; intervention; rehabilitation; exercise; nutrition; metabolism; behavioral modification1. Introduction Chronic spinal cord injury (SCI) is associated with increased risk for cardiometabolic disease (CMD), all-cause cardiovascular disease (CVD), and type 2 diabetes mellitus (...
Multisystem atrophy multisystem coupling Multisystem Developmental Disorder Multisystem disease Multisystem Extension Interface Multisystem eXtention Interface Bus Multisystem Integration Multisystem Integration Facility multisystem network Multisystem Operator Multisystem organ failure ▼Complete...