Despite recent progress in our understanding of the association between the gut microbiome and colorectal cancer (CRC), multi-kingdom gut microbiome dysbiosis in CRC across cohorts is unexplored. We investigated four-kingdom microbiota alterations using CRC metagenomic datasets of 1,368 samples from 8...
Based on this dataset, we built a goat multi-kingdom microbiota catalog (GMMC) consisting 4004 bacterial, 71 archaeal, and 7204 viral genomes, and annotated a total of 4,817,256 non-redundant protein-coding genes. The GMMC genomes contained significant proportions of novel ones, especially ...
The environment, the host and interactions between microorganisms all potentially shape the dynamics of the microbiota, but in such a complex ecosystem, identifying the specific role of any individual factor is challenging10,11,12,13,14. Here we use multi-kingdom absolute abundance quantification, ...
Multi-kingdom microbiota analyses identify bacterial–fungal interactions and biomarkers of colorectal cancer across cohorts 作者: 2881499906@qq.com 免费制作 更多内容Multi-kingdom microbiota analyses identify bacterial–fungal interactions and biomarkers of colorectal cancer across cohorts 发布时间:2023-1-03 ...
Classification of GA based on multi-kingdom signatures Finally, we evaluated the potential of the multi-kingdom signatures (including bacteriome, mycobiome, and virome signatures) of the fecal microbiome for the classification of GA status. Using the random forest model with leave-one-out cross-va...
This difference may be due to the more comprehensive information on the rumen microbiota characterized by metagenomics compared with amplicon sequencing, since multi-kingdom levels including not only bacteria and archaea but also eukaryotes and viruses can be characterized by metagenomic sequencing. In ...
The second step is an a priori nested ANOVA test to the microbiome cladograms and the labels to test for a relation between the label and the microbiota (Fig.1D a priori nested ANOVA). If no significant relation is identified at any taxonomy level, the label is deemed “not microbially ...
Collectively, our findings highlight the potential application of multikingdom and functional gut microbiota markers as non-invasive diagnostic tools in ASD.This is a preview of subscription content, access via your institution Access optionsAccess Nature and 54 other Nature Portfolio journals Get ...
MAGs representing the human microbiota. However, this collection encompasses merely 151 genomes from the vagina16. Consequently, there exists an urgent need to undertake metagenomic-based efforts aimed at establishing an extended reference genome database specifically tailored for the vaginal microbiota. ...
kingdom level was 88.23%; to the phylum level, 85.92%; to the class level, 81.14%; to the order level was 80.76%; to the family level, 67.80%; to the genus level, 64.61%; and the species level, 43.67%. At the phylum level, on the basis of the composition of gut microbiota of ...