The mechanism of mucus production in bronchial asthma. Izuhara K,Ohta S,Shiraishi H,Suzuki S,Taniguchi K,Toda S,Tanabe T,Yasuo M,Kubo K,Hoshino T,Aizawa H. Current Medicinal Chemistry . 2009Izuhara, K., et al., The mechanism of mucus production in bronchial asthma. Curr Med Chem, ...
A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.AbstractAsthma is a major public health burden worldwide. Studies from our group and others have demonstrated that SERPINB3 and SERPINB4 are induced in patients with asthma; however, their mechanistic role in...
Mast cell chymase and cathepsin G are pro-inflammatory mediators that have been implicated in mucus production in asthma 31, 32. Der p1 is a protease found in HDM and the protease activity is important in mediating the allergic response 33. While it is possible that Der p1 is a critical ...
Induction of Airway Mucus Production By T Helper 2 (Th2) Cells: A Critical Role For Interleukin 4 In Cell Recruitment But Not Mucus Production Airway inflammation is believed to stimulate mucus production in asthmatic patients. Increased mucus secretion is an important clinical symptom and contrib....
We tested the hypothesis that (1) mucus production can be included in the cell response to iron deficiency; (2) mucus binds iron and increases cell metal uptake; and subsequently (3) mucus impacts the inflammatory response to particle exposure. Using quantitative PCR, RNA for both MUC5B and ...
In human asthmati... L Cohn,RJ Homer,H Macleod,... - 《Journal of Immunology》 被引量: 1271发表: 1999年 Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology airway epithelial cell hypertrophy with mucus production, and mast cell hyperplasia, similar ...
16.The Preventive Effect of Bacillus Calmette-Guerin Vaccinated in Early Life on Airway Inflammation and Mucus Production in a Juvenile Mouse Model of Asthma;早期接种减毒活菌卡介苗对支气管哮喘幼鼠气道炎症和黏液分泌的预防作用 17.Effects of interleukin-17 on metaplasia of goblet cell and secretion of...
Conclusion CaCC 1 may play an important role inmucusoverproduction in asthmatic airway. 结论CaCC1在哮喘患者气道上皮表达增加,可能与哮喘患者的气道黏液高分泌密切相关. 期刊摘选 Themucusin my nose has dried up and forms dark yellow crusts. 我鼻内粘液干掉结成深黄色硬痂. ...
Fact:Milk consumption does not lead to mucus production or asthma. Does dairy cause mucus? Some early studies designed to test the theory thatdairy products increase mucus production found that it does not. One study measured mucus production by weighing tissues after people blew their noses into...
Mucus production is an important feature of asthma and contributes substantially to morbidity and mortality, especially in more severe disease. Many case reports and autopsy series demonstrate that in most cases of fatal asthma, many of the small airways are completely obstructed with mucus. Goblet ...