A role for the commensal microbiota has been implicated in colon MP differentiation and/or maintenance in several studies, with lower numbers of both monocyte-derived and tissue-resident long-lived MPs present in germ-free (GF) mice,5,6,12,25,26however, a substantial number of mature colon M...
The early stage of the tumor carcinogenesis process is related to immune response changes in cytokine levels, immune cell density, and immune cell function.121 How do pathogens interact with the immune response beyond inducing inflammation? Tregs play a key immune regulatory role during infection and...
Dysbiosis of gut fungal microbiota is associated with mucosal inflammation in Crohn's disease. J. Clin. Gastroenterol. 2014, 48, 513–523. [CrossRef] [PubMed] 37. Sam, Q.H.; Chang, M.W.; Chai, L.Y. The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host. Int. J....
Abstract: Recurrent chronic mucosal inflammation, a characteristic of inflammatory bowel diseases (IBD), perturbs the intestinal epithelial homeostasis resulting in formation of mucosal wounds and, in most severe cases, leads to colitis-associated colon cancer (CAC). The altered structure of epithelial ...