E. (2002) Mucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells. J. Biol. Chem. 277, 6858 - 6863X. Zheng et al., " Mucin-like Domain of Enteropeptidase Directs Apical Targeting in Mardin-Darby Canine Kidney Cells ", The Journal of Biological ...
The domain structure of HEG1 was predicted as follows: signal peptides (exon 1), residues 1–29; proline rich domain (Pro rich) (exon 1), 30–106; serine/threonine rich region (Ser/Thr rich) (exon 2–5), 107–530; Ser/Thr rich (exon 6), 531–630; Ser/Thr rich (exon 7),...
Mucins are large and highly glycosylated proteins and major component of the mucus that coats the lining of epithelial organs. Mucins are characterized by the presence of extended regions rich in the amino acids Proline, Threonine and Serine (PTS domain), where the Serines and Threonines are O...
It encodes a 15.8-kDa protein (after signal peptide removal) containing a typical mucin domain: 86 amino acid residues, 72.1% of which are Ser or Thr, organized into an array of heptameric repeats, interspersed with proline residues. At the C-terminal end of the putative protein are two ...
The domain structure of the identified mucin genes was found to be consistent with the conserved domains found in the homologous proteins of vertebrate species. The discovery of a diverse range of mucin genes in sea anemone species provided a basic reference for future mucin studies in cnidarians ...
They encode secreted, mucin-like proteins with N-terminal Ser/Thr-rich repeats and a C-terminal anchor domain rich in aromatic amino acids. About 75% of the protein molecular masses result from post-translational modifications. The Ser/Thr-rich motifs are supposed to serve as targets for ...
B, in addition to the unique N-terminal domain of 450 amino acids (H domain) and C-terminal domain of 170 amino acids (T domain), the main part of the protein composed of repetitive regions (r1-r12 domains). A unit composed of r3-r5 domains was tandemly repeated three times (R1-R3...
Sequence and biochemical analyses revealed that this gene encodes aBombyx-specific mucin-like glycoprotein with a single transmembrane domain. The NSD-1 protein was specifically expressed in the larval midgut epithelium, the known infection site of BmDV. Sequence analysis of thensd-1gene from 13 ...
The sole hydrophobic domain found on LSLCL corresponded to the first 21 amino acid residues of this protein. The leucine zipper of P47 is particularly prone to form coiled coil structures (19), since it is composed of six heptads with a Leu/Val residue at structural position a and an Ile...
Therefore, the PSGL-1 recognition of L-selectin may depend on the N-terminal sulfated tyrosine domain shown to be required for recognition of P-selectin. To characterize interactions between L-selectin ligand activity on leukocytes and L-selectin expressed on a cell surface rather than immobilized ...