The cloning of mucin cDNAs brought about by the application of molecular biology and molecular analyses constitutes a major step in understanding mucin structure and function. Here two classes of mucins are described: epithelium-associated and endothelium/leukocyte-associated mucins, which have thus far...
However, it has yet to be fully addressed how the physical structure of the mucus gel influences its barrier function and its ability to trap viruses via glycan mediated interactions to prevent infection. To address this, IAV and ... L Kaler,E Iverson,S Bader,... - 《Communications Biology...
J. Structure and function of the cell surface (tethered) mucins. Annu. Rev. Physiol. 70, 431–457 (2008). Article CAS PubMed Google Scholar Henry, S. et al. Structural and immunochemical identification of Le(a), Le(b), H type 1, and related glycolipids in small intestinal mucosa of...
The effect of mucins on the structure and mechanical properties of solid foods is difficult to model, especially when one considers the challenges in monitoring the physicochemical, physiological and neurological processes during their mastication. Liquid emulsions, on the other side, present a very goo...
The structure and function of MUC16 have been well studied, but the mechanisms of regulation ofMUC16expression have yet to be clarified. We have examined the epigenetic status of theMUC165′-flanking region in breast, lung, pancreas, and colon cancer cells using MassARRAY analysis and ChIP assa...
Structure and function of the cell surface (tethered) mucins Annu. Rev. Physiol, 70 (2008), pp. 431-457 10.1146/annurev.physiol.70.113006.100659 17850209 CrossrefView in ScopusGoogle Scholar 10 E.P. Lillehoj, K. Kato, W. Lu, K.C. Kim Cellular and molecular biology of airway mucins ...
[19]Baxter NT, Zackular JP, Chen GY, et al. Structure of the gut microbiome following colonization with human feces determines colonic tumor burden[J]. Microbiome, 2014, 2: 20. DOI:10.1186/2049-2618-2-20 [20]Meng X, ...
Figure 1: The structure and function of MUC7. (a) Genomic location, organization and subexonic copy number variation of the MUC7 gene in the human reference genome (GRCh37/hg19). The gray bar indicates the chromosomal band (q13.3) where MUC7 resides. The zoomed-in version of the gene ...
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A. Structure and function of the polymeric mucins in airways mucus. Annu. Rev. Physiol 70, 459–486 (2008). 3. Corfield, A. P. Mucins: A biologically relevant glycan barrier in mucosal protection. Biochim. Biophys. Acta - Gen. Subj. 1850, 236–252 (2015). 4. Danahay, H. et al....