口腔颌面外科杂志2013axillofacialSurgeryVo1.23August,2013MTR多态性与非综合征性唇腭裂的关联性研究山西医科大学第一医院口腔科,山西太原03000[摘要]目的:研究蛋氨酸合成酶(methioninesvnthase,MTR/MS)~rs1805087位点单核苷酸多态性与山西人群非综合征性唇腭裂(NSCL/P)的相关性。方法用聚合酶链式反应一限制性片段长度...
methyhransferase,MTR)SNPs位点Rs1805087多态性与非综合征性唇腭裂的关系。方法 采用聚合酶链反应一限制 性片段长度多态性方法,检测174例非综合征性唇腭裂患者和169例正常对照组的MTR基因Rs1805087的多态 性。结果 MTR基因Rs1805087位点基因型频率分布符合Hardy—Weinberg平衡;MTR基因Rs1805087位点基因 ...
结论结果未显示MTR基因Rs1805087多态性与非综合征性唇腭裂的发生有关。王江波山西医科大学第一医院南欣荣山西医科大学第一医院北京口腔医学王江波.MTR基因rs1805087多态性与非综合征性唇腭裂的相关性研究[D]. 山西医科大学 2011王江波;南欣荣.MTR基因Rs1805087多态性与非综合征性唇腭裂的相关性研究.北京口腔医学....
In this study, we performed a meta-analysis to evaluate the association between polymorphisms of MTHFR C677T (rs1801133), MTHFR A1298C (rs1801131), MTRR A66G (rs1801394) and MTR A2756G (rs1805087) and the risk of male infertility. The study population included not only fertile and infe...
目的:研究蛋氨酸合成酶(methioninesvnthase,MTR/MS)~因rs1805087位点单核苷酸多态性与山西人群非 综合征性唇腭裂(NSCL/P)的相关性。方法:采用聚合酶链式反应一限制性片段长度多态性(PCR—RFLP)方法对135 个NSCL/P核心家庭、150例正常新生儿及其母亲的MTR基因rs1805087位点多态性进行检测;用人群关联研究、病 ...
(ICP-MS)检测;MTHFR rs1801133和MTR rs1805087基因型采用基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF-MS)方法,在Sequenom平台检测.[结果]病例组和对照组尿碑含量差异无统计学意义(P=0.32).rs1801133和rs1805087在病例组和对照组中基因型分布差异无统计学意义(P>0.05).rs1801133和rs 1805087与砷对乳腺癌发生...
Conventional PCR amplification was carried out for resolving angiotensin converting enzyme 'ACE' insertion/deletion (I/D) polymorphism (rs4646994). ANOVA analysis, adjusted for the covariates, revealed that rs1801133, rs1805087 polymorphisms and homocysteine levels were associated with CAD. Logistic ...
TheC allele of rs1770449 (OR = 1.961, 95%CI: 1.379–2.788) and theA allele of rs1050993 (OR = 1.994, 95%CI: 1.401–2.839) in infants were associated with an increased risk of CHDs. Over-transmission of SNPs rs1770449 and rs1050993 and haplotype CAA (rs1770449-rs1805087-rs...
Some common polymorphisms (MTHFR C677T, rs1801133; MTHFR A1298C, rs1801131; MTR A2756G, rs1805087; and MTRR A66G, rs1801394) may influence the serum folate level [6,7,10,18]. Numerous studies have demonstrated that the MTHFR C677T mutation significantly lowers the serum folate level [...
Some common polymorphisms (MTHFR C677T, rs1801133; MTHFR A1298C, rs1801131; MTR A2756G, rs1805087; and MTRR A66G, rs1801394) may influence the serum folate level [6,7,10,18]. Numerous studies have demonstrated that the MTHFR C677T mutation significantly lowers the serum folate level [...