Lewis, T. Lightfoot, Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review, Am. J. Epidemiol. 165 (2007) 1-13.Gilbody S, Lewis S, Lightfoot T: Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE ...
Methylenetetrahydrofolate Reductase (MTHFR) Genetic Polymorphisms and Psychiatric Disorders: A HuGE Review The authors performed a meta-analysis of studies examining the association between polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) ge... G Simon,L Sarah,L Tracy - 《American...
Folate-mediated one-carbon metabolism and its effect on female fertility and preg- nancy viability[J]. Nutr Rev, 2010, 68(2):99 -113. [3] Gilbody S, Lewis S, Lightfoot T. Methylenetetrahydrofolate reduc- tase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review [J]. ...
folate reductase deficiency (MTHFRD) [MIM:236250]: Autosomal recessive disorder with a wide range of features including homocysteinuria, homocysteinemia [MIM:603174], developmental delay, severe mental retardation, perinatal death, psychiatric disturbances, and later-onset neurodegenerative disorders. ...
Gilbody S et al. Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. Am J Epidem. 2007; 165:1-13. Lewis SJ et al. The thermolabile variant of MTHFR is associated with depression in the British Women’s Heart and Health Study and a meta...
ISSN (Electronic):1872-7123 ISSN (Print):0165-1781 Publication date (Electronic):Jan 30 2014 Volume: 215 Issue: 1 Affiliations [1]Department of Biomedical Science, College of Life Science, CHA University, 222 Yatapdong, Bundanggu, Seongnamsi, Gyeonggido 463-836, Republic of Korea. ...
(preeclampsia), an eye disorder called glaucoma, psychiatric disorders, and certain types of cancer. The 677C>T polymorphism in the MTHFR gene has also been suggested as a risk factor for cleft lip and palate, a birth defect in which there is a split in the upper lip and an opening in...
P.3.015 Hyperhomocysteinemia, methylenetetrahydrofolate reductase 677C→T polymorphism and psychiatric disorders in children Picture 1 The mean level of Hcy (μmol/L) in patients with affective disorders and Results Theaverage level of Hcy was 11.94±5.6 μmol/L for patients with schizophrenia's ...
Over the last two decades there has been considerable interest in the role of the B vitamins, folic acid and vitamin B12 for the normal function of the brain. Early studies showed that a deficiency in these vitamins is associated with a number of neurological and psychiatric disorders including...
During the disease course, symptoms were almost exclusively neurological with cognitive dysfunction (93%), gait disorders (86%), epilepsy (71%), psychiatric symptoms (57%), polyneuropathy (43%), and visual deficit (43%). Mean diagnostic delay was 14 years. Vascular events were observed in 28...