Association of a missense nucleotide polymorphism in the MT-ND2 gene with mitochondrial reactive oxygen species production in the Tibet chicken embryo incubated in normoxia or simulated hypoxia. WANG X Y,HE Y,LI J Y, et al. Animal Genetics . 2013...
生物信息学 蛋白别名:NADH dehydrogenase subunit 2; NADH-ubiquinone oxidoreductase chain 2 基因别名:MT-ND2; MTND2; NADH2; ND2 UniProt ID:(Human) P03891,(Rat) P11662,(Mouse) P03893 Entrez Gene ID:(Human) 4536,(Rat) 26194,(Mouse) 17717...
基因简称(symbol) MTND2P16 [HGNC] [GeneCards] [NCBI] 基因种类(locus group) pseudogene 同源简称(alias symbol) 基因家族代码(gene_family_id) [HGNC] [GenScript] omim代码 entrez码 100873347 [Vega] ensembl基因码 ENSG00000230818 [Ensembl] 基因家族(gene family) refseq数据库代号 NG_032428...
Mutations in mtDNA are not commonly associated with susceptibility or resistance to autoimmune type 1 diabetes (T1D) in humans, although a recently reported C5178A transversion resulting in a leucine to methonine substitution in the mt mt-Nd2 gene has been associated with protection from T1D in...
The results showed that mt-ND2 gene was expressed in the 15 tissues of hybrid chickens with the highest level in heart and lowest level in pancreas tissue; 30% energy restriction did not significantly affect mt-ND2 mRNA level in chicken liver tissue. Both the mt-ND2mRNA levels in chicken ...
To date, only few mutations in the mitochondrial DNA (mtDNA)-encoded ND2 subunit of Complex I have been reported, usually presenting a severe phenotype characterized by early onset encephalomyopathy and early death. In this report, we describe a new mutation in theMTND2gene in a 21-year-old...
Reactive oxygen species (ROS) play a critical role in the pathogenesis of human diseases. A cytosine to adenine transversion in the mitochondrially encoded NADH dehydrogenase subunit 2 (, human; , mouse) gene results in resistance against type 1 diabetes and several additional ROS-associated ...
Shared alleles of mt-Co3 and mt-Tr comparing NOD and ALR allowed for exclusion of these two genes as candidates, implicating the mt-Nd2 variation as a potential ALR-derived type 1 diabetes protective gene. CONCLUSIONS/INTERPRETATION: The unusual resistance of ALR mice to both ROS-mediated and...
Determining the Matrilineal Origin of Indonesian Kerinci Duck Breed (Anas platyrhynchos) Based on MT-ND2 Gene Diversitydoi:10.4308/hjb.31.3.581-588DepisonPutra, Widya Pintaka BayuGushairiyantoGunawan, AsepSumantri, CeceHAYATI: Journal of Biosciences...
Objective-to investigate whether a single nucleotide polymorphism (snp) in the mitochondrial gene for nadh dehydro-genase 2 (mt-nd2} can modulate susceptibility to type 1 diabetes in nod mice. Research design and methods-nod/shiltj mice conplastic for th...