The MSTN and FGF5 dual-gene editing also resulted in the inhibition of nucleotide metabolism and TCA cycle pathway in differentiated myotube cells. The differential metabolites we identified can be characterized as biomarkers of different cellular states, and providing a new reference for MSTN and ...
一种利用CRISPR/Cas9系统共同敲除山羊MSTN和FGF5基因的方法 Utilizing CRISPR / Cas9 systems together, knocking out the genes of the MSTN and FGF5一种利用CRISPR/Cas9系统共同敲除山羊MSTN和FGF5基因的方法 Utilizing CRISPR / Cas9 systems together, knocking out the genes of the MSTN and FGF5本发明提供了一...
成纤维细胞生长因子5(FGF5) Fibroblast Growth Factor 5 嵌套蛋白(NES) Nestin 碳酸酐酶Ⅵ(CA6) Carbonic Anhydrase VI 透明质酸合酶2(HAS2) Hyaluronan Synthase 2 */*丰富端*丰富重复蛋白(PRELP) Proline Arginine Rich End Leucine Rich Repeat Protein 丝聚蛋白(FLG) Filaggrin 血小板反应蛋白解整合素...
meat;MSTN;FGF5;sheep;90-day feeding;rat 1. Introduction Myostatin (MSTN), also called growth and differentiation factor-8 (GDF-8), is a member of the transforming growth factor-β (TGF-β) superfamily that negatively regulates skeletal muscle development and growth. Natural mutations in theMSTN...
Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system. Sci. Rep. 2015, 5, 13878. [Google Scholar] [CrossRef] [Green Version] Wang, L.; Cai, B.; Zhou, S.; Zhu, H.; Qu, L.; Wang, X.; Chen, Y. RNA-seq reveals transcriptome ...