The structure of this inhibitor, WM-S1-030, was based on a conformationally constrained 2-pyridone structure (Fig. 1A). A docking study was performed using a homology model established by ORCHESTRAR of Sybyl X-2.1.1 (Tripos, Inc.), using the crystal structure of c-MET (PDB code: 3F82)...
c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev 2003;22:309–325. 14 Benvenuti S, Comoglio PM. The MET receptor tyrosine kinase in invasion and metastasis. J Cell Physiol 2007;213:316–325. 15 Comoglio PM, Giordano S, Trusolino L. Drug develop-...
Structure Filter Element/Assy Filtration Grade Hepa Filter Application Liquid Pattern Dry Brand Green Filter Classification Oil Filter Transport Package According to Customer′s Requirement Specification 1 3/8-12 UNF-2B Trademark Green Filter Origin Wenzhou HS Code 8421230...