MSI-1436 (Trodusquemine) 是一种选择性的、非竞争性的蛋白酪氨酸磷酸酶 1B (PTP1B) 抑制剂,其 IC50 约为 1 μM,比 TCPTP 高 200 倍 (IC50, 224 μM) . 此产品仅用于科学研究,我们不为任何个人用途提供产品和服务 库存:现货 可选规格
(Synonyms:Trodusquemine; Aminosterol-1436) 目录号 : KM10176 CAS No. : 186139-09-3 纯度: ≥95% Data Sheet 产品使用指南 MSI-1436 是具有选择性的 PTB1B 的非竞争性抑制剂,其 IC50 为1 μM,而对 TCPTP 的 IC50 值为224 μM。
关键词标签:Trodusquemine 产品完善度: 产品详情 MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。 MSI-1436 CAS No. : 186139-09-3 MCE 站:MSI-1436 产品活性:MSI-1436 是具有选择性的 PTB1B 的非竞争性抑制剂,其 IC50 为1 μM,而对 TCPTP 的 IC50 值为224 μM。
产品编号 T12116 别名Trodusquemine, Aminosterol-1436Cas号 186139-09-3 MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM) 规格价格库存数量 25 mg ¥ 17,280 8-10周 50 mg ¥ 27,680 8-10周 100 mg ¥ 44,280...
MSI-1436 (Trodusquemine) exhibits anxiolytic effect through a restoration of endocannabinoid (eCB) signaling within the amygdala[2]. MSI-1436 (5 mg/kg, i.p.) has an anti-diabetic effect on diabetic mice, and is sufficient to suppress food intake and cause weight loss in CD1 mice[3]. ...
Genaera Corporation,Plymouth Meeting,Pa.,has announced that the investigational new drug (IND) application submitted to the US Food and Drug Administration (FDA) for trodusquemine (MSI-1436) in type 2 diabetes is now in effect.This application represents the second IND filed by the company in...
1www.glpbio.com Product Name:MSI-1436 (Trodusquemine)Cat. No.:GC32396 Chemical Properties Cas No.186139-09-3Chemical Name N/A Canonical SMILES NCCCNCCCCNCCCN[C@@H]1C[C@@](C[C@@H](O)[C@]2([H])[C@]3([H])CC[C@@]4(C)[C@@]2([H])C C[C@@]4([C@H](C)CC[C@@H...
Trodusquemine, also known as MSI-1436 and MSI-1436C, is a protein tyrosine phosphatase PTP-1B inhibitor potentially for the treatment of type 2 diabetes. Trodusquemine significantly enhanced insulin-stimulated tyrosine phosphorylation of insulin recepto
中文名称:MSI-1436 英文名称:Trodusquemine CAS No.:186139-09-3 分子式:C37H72N4O5S 分子量:685.0564 了解化合物详情 快速询单国内供应商 MSI-1436 数据 Mol: 186139-09-3.mol by:chem960.com ChemDraw08031019472D ……… 000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000...
MSI-1436 (Trodusquemine) exhibits anxiolytic effect through a restoration of endocannabinoid (eCB) signaling within the amygdala[2]. MSI-1436 (5 mg/kg, i.p.) has an anti-diabetic effect on diabetic mice, and is sufficient to suppress food intake and cause weight loss in CD1 mice[3]. ...