Figure S1: Characterization of MSC-EV preparations by Western blot, Figure S2: General gating strategy to define T cell subpopulations in PBMC, Figure S3: Overview of the analysis strategy to determine the cytokine response of T cell subsets, Figure S4: Influence of MSC-EVs on TN and TCM ...
In general, nucleic acid-based drugs, such as antisense oligonucleotides, small interfering RNA (siRNA), and microRNA (miRNA), are enzymatically unstable in the serum due to nucleases. Endogenous miRNAs released from cells are protected within exosomes in the bloodstream. Similarly, MSCs can be ...