Topics discussed include magnetic resonance images (MRI) presented by the studies demonstrating the way MS-associated spinal cord abnormalities manifest and progress over time, Hugh Kearney and colleagues examining whether spinal meninges can be measured in vivo in one study and Carsten Lukas and ...
2.两次或两次以上发作,但体检上累及中枢神经系统同一部位,需符合MRI空间上的诊断标准,若脑脊液检查阳性,MRI标准可以放宽。 3.一次发作,且有中枢神经系统两个部位受累的客观体征,需符合MRI时间上的诊断标准。 4.一次发作,且中枢神经系统仅有一个部位受累的客观体征,需符合MRI时间及空间上的诊断标准。 5.一次发作症状...
Topics discussed include magnetic resonance images (MRI) presented by the studies demonstrating the way MS-associated spinal cord abnormalities manifest and progress over time, Hugh Kearney and colleagues examining whether spinal meninges can be measured in vivo in one study and Carsten Lukas and ...
1、The role of MRI in the diagnosis of Multiple Sclerosis,MS-主要讨论问题,典型MRI发现 McDonald标准:MRI在诊断的应用 鉴别诊断: MS-其他常见白质病变,当我们见下面病例,首先考虑是什么病?MS?高血压性小血管病?或其他更少见病,白质脑病: 许多神经系统疾病在临床和放射学均与MS相似 多数意外发现WMLs常为血管...
近几年,脑容量变化,神经丝轻链、认知功能评估等也逐渐成为可能的观察指标。冯慧宇教授表示,鉴于目前脑容量变化和神经丝轻链等指标在临床上较难评估,因此临床常用的NEDA定义为NEDA-3,即实现无临床复发、无确证残疾进展、磁共振成像(...
19.Sastre-Garriga J, Pareto D, Battaglini M, et al. MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice. Nat Rev Neurol, 2020, 16(3): 171-182. 20.Zivadinov R, Tava...
In the case ofmultiple sclerosis (MS), MRI scans are done of the brain and sometimes spinal cord to spot damage to, or lesions on, portions of the myelin sheath, a fatty coating that protects nerve cell fibers, or axons. “MRI is critical in thediagnosis of MS,” saysRobert Zivadinov...
MRIFilippi M, Rocca MA.doi:10.1038/nrneurol.2013.40Massimo FilippiMaria A RoccaNature Reviews NeurologyFilippi M., Rocca M.A. Multiple sclerosis: Linking disability and spinal cord imaging outcomes in MS. Nat. Rev. Neurol. 2013; 9 :189–190. doi: 10.1038/nrneurol.2013.40. [ Cross Ref ]...
to diagnose MS and rule out other causes of symptoms. More than 90% of people with MS have scar tissue that shows up on anMRI scan. A spinal tap can check for abnormalities in the fluid that bathes the brain and spinal cord. Tests to look at electrical activity of nerves can also hel...
起初MS治疗侧重于减少复发次数,随着影像学技术发展,MRI的影像学指标逐渐被加入评价标准。为更全面反映疾病活动和药物的疗效,2014年首次提出“无疾病活动证据(NEDA)-3”,即无复发、无确认的残疾进展、无MRI活动病灶5,随后被用于多项Ⅲ期临床研究。但NEDA-3更倾向...