PebodyR.RooneyC.Elsevier B.V.International Journal of Antimicrobial AgentsPotz N, Powell D, Lamagni T, et al. Mortality following invasive MRSA infection in England, 2004 -5. In: Proceedings of the 17th European Congress of Clinical Microbiology and Infectious Diseases; March 31, 2007; Munich...
(MIC, 8 g/ml) Infection in the USPatient no./Source VancomycinTherapyOutcomeAge exposure (wk)1 (59)Peritonitis 18TMP-SMZ, RIF IC (died)2 (66)Bacteremia 18GM, RIF IC (died)3 (79)Bacteremia 6VAN, TOB Died4 (63)Bacteremia, IE 3.5VAN, TOB, RIF Died5 (56)Bacteremia, OM 18VAN,...
An investigation of mutations among isolates within the index case sheds light on the evolution of the pathogen over the course of infection. We identified that the population present in the lymph node of the index case all had one of two different mutations causing inactivation of the same ...
Patients with MRSA bacteremia were evaluated for date, duration, epidemiologic source and number of positive blood cultures, source of infection, clinical signs of IE, presence of vascular events (emboli, hemorrhage), hemodialysis dependency, short-term catheter, implantable catheter, fistula or graft...
aureus infection in a mouse bacteraemia model, thereby helping to establish FtsZ as an antibacterial drug target [14]. Crystallography studies have revealed that PC190723 binds into the narrow, hydrophobic pocket within the interdomain cleft of S. aureus FtsZ described above [7]. Structure-...