7.Wilson E, Goswami J, Baqui AH, et al. Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults. N Engl J Med. 2023;389(24):2233-2244. doi:10.1056/NEJMoa2307079
Moderna正在评估编码融合前F蛋白的三种单剂量候选疫苗:mRNA-1172和mRNA-1777用于成人,以及mRNA-1345用于儿童。在I期临床试验中,mRNA-1777诱导RSV中和抗体产生强烈的体液反应,CD4+T细胞对RSV F蛋白产生反应,且无严重不良事件。mRNA-1345的序列已被进一步设计和密码子优化,以增强相对于mRNA-...
1.Moderna Receives U.S. FDA Approval for RSV Vaccine mRESVIA(R) (http://modernatx.com) 2.Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults | New England Journal of Medicine (http://nejm.org) 3.ASCO (http://q4cdn.com) 4.Combination therapy of KRAS G12V mRNA ...
[3] Nussbaum J, Cao X, Railkar RA, et al. Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults. Vaccine. 2023 Oct 20;41(44):6488-6501. [4] Wilson E, Go...
8.https://www.cidrap.umn.edu/respiratory-syncytial-virus-rsv/cdc-panel-revises-rsv-vaccine-recommendations-adults 免责声明：本文旨在传递生命科学和医疗健康产业最新讯息，不代表平台立场，不构成任何投资意见和建议，以官方/公司公告为准。本文也不是治疗方案推荐，如需获得治疗方案指导，请前往正规医院就诊。
1..com/news/news-details/2024/Moderna-Receives-U.S.-FDA-Approval-for-RSV-Vaccine-mRESVIAR/default.aspx 2. Fowler et al. ,Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma.Sci. Transl. Med.16,eadg9814(2024)...
1.Moderna Receives U.S. FDA Approval for RSV Vaccine mRESVIA(R) (modernatx.com) 2.Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults | New England Journal of Medicine (nejm.org) 3.ASCO (q4cdn.com) 4.Combination therapy of KRAS G12V mRNA vaccine and pembrolizumab:...
Moderna的RSV疫苗获批，是mRNA技术发展史上的一个重要里程碑。它不仅为老年人群提供了新的保护，也为mRNA技术在未来疫苗开发中的应用展示了广阔前景。随着mRNA技术的不断进步，我们有理由相信，这一创新技术将在医疗健康领域发挥更加重要的作用。参考 Moderna Receives U.S. FDA Approval for RSV Vaccine mRESVIA(R)
7.Wilson E, Goswami J, Baqui AH, et al. Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults. N Engl J Med. 2023;389(24):2233-2244. doi:10.1056/NEJMoa2307079 免责声明:本文旨在传递生命科学和医疗健康产业最新讯息,不代表平台立场,不构成任何投资意见和建议,以官方/公司公告...
4.https://www.gsk.com/en-gb/media/press-releases/gsk-shares-positive-data-for-arexvy-its-respiratory-syncytial-virus-older-adult-vaccine-indicating-protection-over-two-rsv-seasons/ 5.https://www.cidrap.umn.edu/respiratory-syncytial-virus-rsv/early-safety-data-rsv-vaccines-show-rare-guillain-ba...