Objectives The COVID-19 pandemic has exposed a number of key challenges that need to be urgently addressed. Mass spectrometric studies of blood plasma proteomics provide a deep understanding of the relationship between the severe course of infection and
Initial testing on the QQQ revealed that the [M + 2H]2+ ion of the qPLPDccR (q = pyroGlu, c = carbamidomethyl cysteine) peptide gave the highest intensity, and the transitions y6, y5, y4, y3 and b2 (fragment ions) were used to develop the MRM assay in the QQQ. The QQQ workfl...
Antibiotic therapy, DNA, Metagenomic screeningDetermining the effects of antimicrobial therapies on airway microbiology at a population-level is essential. Such analysis allows, for example, surveillance of antibiotic-induced changes in pathogen prevalence, the emergence and spread of antibiotic resistance, ...
Obstructive sleep apnea (OSA) is highly prevalent in the general population, and occurs at all ages [1]. OSA is characterized by collapse of upper airways during sleep with ineffective respiratory efforts, intermittent hypoxia and sleep disruption. Continuous positive airway pressure (CPAP), mandibula...