These mice showed a high IgG4 concentration in the sera and increased populations of IgG4-positive plasma cells and CD3 B220 CD138 T cells in the spleen. Moreover, these mice showed aggravated inflammation in organs, such as the salivary glands and stomach. T...
Soluble syndecan I (CD138) released by MRL/Lpr T cells enhances APRIL-mediated lupus B cell survival and differentiationHigh level of soluble serum syndecan-1 (CD138), a heparan sulfate–bearing proteoglycan, in systemic lupus erythematosus (SLE) patients correlates with disease activity and lupus...
Circulating CD138 (syndecan-1) enhances APRIL-mediated autoreactive B cell survival and differentiation in MRL/Lpr micedoi:10.1101/2021.05.11.443667Liu LAkkoyunlu MCold Spring Harbor Laboratory