Fast Recovery Fast Spin Echo (FRFSE): is an extension of the Fast spin Echo sequence and incorporates an additional refocusing pulse and 90 degree excitation at the end of the echo train. This additional forced recovery of the long T1 and T2 spins increases T2 contrast with shorter acquisitions...
Beside the intrinsic relaxometric properties of the molecules, their effect on the MRI signal intensity is modified by their compartmentalization. In particular, the sequestration of iron nanoparticles in the reticuloendothelial cells dramatically reduces the T1 relaxivity while enhancing their T2/T2* rel...