White matter changeMRIBlood pressureObstructive sleep apnea (OSA) is nowadays introduced as a risk factor for white matter brain changes. Research on OSA and white matter changes provides contradictory evidence for the contextual link between the two conditions. This study aimed to determine the ...
Researchers atYale Universityanalyzing specialized MRI exams found significant changes in the microstructure of the brain’s white matter in adolescents and young adults withautism spectrum disorder(ASD) compared to a control group, according to research being presented next week at the annual meeting o...
This article reviews the use of white-matter changes as identified on MRI as a surrogate marker in clinical trials on vascular dementia. As of yet, insufficient evidence is present to implement rating or volumetric assessment of the burden of white-matter changes as surrogate marker in such trial...
There is a clinical interest in identifying normal appearing white matter (NAWM) areas in brain T2-weighted (T2W) MRI scans in multiple sclerosis (MS) subjects. These areas are susceptible to disease development and areas need to be studied in order to find potential associations between texture...
"The two groups differ when it comes to brain white matter structure. This can be one of the causes of theneurological problemsexperienced by the group that had suffered from severe COVID-19. It's a result that's in line with other studies that have shown changes to the brain's white ...
Predicting the evolution of white matter hyperintensities (WMH), a common feature in brain magnetic resonance imaging (MRI) scans of older adults (i.e., whether WMH will grow, remain stable, or shrink with time) is important for personalised therapeutic interventions. However, this task is ...
Numerous factors such as cognitive reserve, concomitant loss of brain volume, and ultrastructural changes have been identified as mediators between white matter damage and clinical findings, and need to be incorporated in the consideration of WMLs as visible markers of these detrimental processes. 展开...
[24]Zhou J, Greicius MD, Gennatas ED, et al. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease[J]. Brain, 2010, 133(Pt 5): 1352-1367. DOI: 10.1093/brain/awq07...
We aimed to evaluate whether white and gray matter microstructure changes observed with magnetic resonance imaging (MRI)-based diffusion tensor imaging (DTI) can be used to reflect the progression of chronic brain trauma. The MRI-DTI parameters, neuropat
CSF biomarker and PIB-PET–derived beta-amyloid signature predicts metabolic, grey matter and cognitive changes in nondemented subjects Beta-amyloid (Aβ) is a histopathological hallmark of Alzheimer's disease dementia, but high levels of Aβ in the brain can also be found in a substantial .....