Parkinson's diseaseDeep Brain StimulationMRI guided Focused UltrasoundBackground Whilst MRI guided Focused Ultrasound (MRgFUS) thalamotomy is an effective treatment option for tremor disorders, there are reports of tremor recurrence in patients with tremor dominant Parkinson''s disease (PD). The ...
The company's Exablate Neuro platform focuses sound waves, safely guided by MRI, to provide tremor treatment to patients with medication-refractory essential tremor and tremor-dominant Parkinson's disease as well as treatment of medication-refractory moderate to severe motor complications of Parkinson'...
Introduction: ExAblate received FDA approval for treatment of a range of movement disorders in 2016, including tremor-dominant Parkinson's disease (TDPD), dyskinetic PD, and essential tremor. This incisionless device allows for magnetic resonance-guided focused ultrasound (MRgFUS) for ablation of ...
guided by MRI, to provide tremor relief to patients with Essential Tremor and Tremor-dominant Parkinson’s Disease. Research for future applications in the neuroscience space is underway
PARKINSON'S diseaseTREATMENT effectivenessHIGH-intensity focused ultrasoundPATIENT monitoringFINGERSELECTROPORATIONIn this paper, a new combined approach, based on Magnetic Resonanceguided Focused Ultrasound Surgery (MRgFUS) technique and functional Near Infrared Spectroscopy (fNIRS), was applied f...
Tremor-dominant Parkinson’s diseasemagnetic resonance imaging-guided focused ultrasound (MRgFUS)voxel-based morphometry (VBM)gray mattercerebellumBackground: Regional differences in gray matter volume (GMV) have been reported to be a reliable marker for diagnosing Parkinson's disease (PD). This study...
Parkinson’s diseaseEssential tremorFunctional neurosurgeryLesioning surgeryMRI-guided focused ultrasound (MRgFUSBACKGROUND: Tremor is a disabling condition, common to several neurodegenerative diseases. Lesioning procedures and deep brain stimulation, respectively, of the ventralis intermedius nucleus for ...
The Unified Parkinson's Disease Rating Scale (UPDRS), global improvement questionnaires and adverse events were assessed at baseline and the most recent follow-up visit (range 2–13.5 months).Results: Twelve patients underwent unilateral MRgFUS VIM thalamotomy. Two patients had transient improvement...
PARKINSON'S diseasePROGNOSISPurpose: This study aimed to identify possible prognostic factors determining early tremor relapse after Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) thalamotomy in patients with essential tremor (ET) and Parkinson's disease (PD). Metho...
MRgFUSFunctional neurosurgeryInterventional neuroradiologyTremor is a common and very disabling symptom in patients with essential tremor and Parkinson's disease. In the recent years, transcranial ablation of thalamic nuclei using magnetic resonance guided high-intensity focused ultrasound has emerged as a ...