2、液体样本：主要是血液，也包括胸腔积液、腹腔积液等。血液样本获取相对方便、创伤小，可多次重复采集，其中的循环肿瘤细胞(CTC)、循环肿瘤DNA(ctDNA)等都可作为 MRD 检测的标志物，能反映全身肿瘤细胞的情况。对于肿瘤患者而言,微小残留病灶(MRD)检测有何临床价值 预测复发 MRD检测阳性结果与癌症复发/再发(CIR)的...
新加坡2025年4月21日 /美通社/ -- Gene Solutions 是一家致力于推动亚洲精准肿瘤学发展的生物技术公司,在此宣布在《JCO Oncology Advances》 发表了一项开创性的真实世界研究成果,验证了 ctDNA 是一种强有力的预后生物标志物,可在癌症管理期间有效监测患者。 K-TRACK™ 是一项基于循环肿瘤DNA(ctDNA)技术的突破...
NCCN 临床实践指南更新(2025 V1)纳入 MRD 相关重要信息:在 B 细胞淋巴瘤领域,对于一线治疗结束时正电子发射断层扫描(PET)呈阳性的弥漫大 B 细胞淋巴瘤(DLBCL)患者,新增循环肿瘤 DNA(ctDNA)检测用于 MRD 评估[1-2]。此次更新为临床医生在相关癌症...
对于在靶向和局部巩固治疗后放射学上无法检测的晚期非小细胞肺癌(NSCLC),ctDNAMRD指导的药物假期策略,有助于减轻患者的经济负担,减少患者用药的毒副作用,延迟耐药时间并改善生存质量。 2024年6月13日,《JAMA肿瘤学》发表了中国研究团队开展的一项“针对ctDNA-M...
Clinical Testing Services 临床检测服务 YuceOne®Monitor 套餐YuceOne®MRD YuceOne®MRD YuceOne®MRD 本检测根据全外显子(WES)检测为患者定制个体化ctDNA监测panel, 采⽤⽬标基因捕获⼆代测序(NGS)技术,全⾯精准地检测与肿瘤发⽣发展或临床治疗相关的基因变异,为肿瘤患者的术后复发风险,及药物疗效...
2. Webinar #3: Opportunities and Challenges Toward the Clinical Application of ctDNA MRD Testing in Solid Cancers. Speaker: Everett Moding, MD PhD. Date: Tuesday September 28, 2021 at 2:00pm Eastern. Meeting: Utility of Cell-free DNA in the Clinic: Current State and Future Directions ...
1. An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nat Med. 2014 May;20(5):548-54. doi: 10.1038/nm.3519. 2. Webinar #3: Opportunities and Challenges Toward the Clinical Application of ctDNA MRD Testing in Solid Cancers. Speaker: Everett Moding, ...
Senior Clinician and the Clinical Director of the Lymphoid Malignancies Branch of the Center for Cancer Research.2“The inclusion of ctDNA testing in the NCCN Guidelines gives us a powerful tool to address both challenges – providing guidance when biopsy isn't p...
2、Webinar #3: Opportunities and Challenges Toward the Clinical Application of ctDNA MRD Testing in Solid Cancers. Speaker: Everett Moding, MD PhD. Date: Tuesday September 28, 2021 at 2:00pm Eastern. Meeting: Utility of Cell-free DNA in the Clinic: Current State and Future Directions ...
2. Webinar #3: Opportunities and Challenges Toward the Clinical Application of ctDNA MRD Testing in Solid Cancers. Speaker: Everett Moding, MD PhD. Date: Tuesday September 28, 2021 at 2:00pm Eastern. Meeting: Utility of Cell-free DNA in the Clinic: Current State and Future Directions ...