In support of this model, we found that elimination of intermolecular disulfides and disruption of ionic interactions at the proposed dimerization interfaces are required to abrogate the ability of CRTDel52 to induce cytokine-independent proliferation of Ba/F3 cells via Mpl. Based on docking studies...
In support of this model, we found that elimination of intermolecular disulfides and disruption of ionic interactions at the proposed dimerization interfaces are required to abrogate the ability of CRTDel52 to induce cytokine-independent proliferation of Ba/F3 cells via Mpl. Based on docking studies...
McCarty JM, Melone PD, Simanis JP, Kanamori D, Dessypris EN, Warshamana-Greene GS. A preliminary investigation into the action of anagrelide : thrombopoietin-c-Mpl receptor interactions. Exp He- matol 2006 ; 34 : 87-96.McCarty JM, Melone PD, Simanis JP, Kanamori D, Dessypris EN, Wars...