This thesis aims to understand the relationship between receptive field structure and functional properties in two prominent visual centers--the superior colliculus (SC) and the primary visual cortex (V1), using extracellular, single-unit recordings in anesthetized mice.Sarnaik, Rashmi...
A red filter was inserted into the path and a red light (617 nm) used to evenly illuminate V1. The stimulus presented in all experiments spanned the central 30° of the mouse’s visual field and consisted of a contrast modulated sweeping noise stimulus periodically every 20 s. Each ...
Contribution of somatostatin- and parvalbumin-expressing interneurons to feature specific surround suppression in mouse V1The responses of V1 neurons to stimuli in the receptive field(RF) can be modulated by stimuli outside the RF. The surround modulation often manifests as surround suppression, and...
(V1) are functionally organized to meet this challenge remains unclear. Combining intrinsic signal optical imaging and single-unit recording, we found that the cutoff SF was much greater for neurons whose receptive fields were located above the mouse. Specifically, we discovered that the cutoff SF...
作者: V Bonin 摘要: Sensory stimuli are processed through individual neurons receptive fields. These receptive fields have historically been measured from electrical recordings, which provide little information about the location of the recorded neurons, and only sparsely sample local populations. As a ...
Here, we use an unbiased approach to quantitatively characterize brain-wide projections to V1 using retrograde tracing. Higher visual areas (HVAs) are known to provide feedback inputs to V1 and modulate receptive field properties, especially in the surround field in mouse and other species (...
NOD/SCID mice are host that are more receptive to the proliferation of human leukemia, however, the high transplantation rate of T-ALL cells suggests that this model fails to identify risk groups, and the researchers found that human-derived T-ALL cells appear to be more readily transplanted ...
aSchematic plot of the widefield imaging setup. Top, an example of a texture image (100° diameter) and the stimulus presentation times. Right, a representative example of the right posterior cortex of a mouse with main-area borders (gray lines). V1, primary visual cortex; LM, secondary ...
contrasting their UV preference for center and full-field responses. This resulted in color-opponent center-surround receptive fields (RFs) and color-opponent full-field responses (Figs.1j, k,2a; SCfull-field < −1;n = 937/1329). A small number of these color-opponent cones in...
Single wide dynamic range (WDR) neurons receiving inputs from the hind paw were isolated in the ipsilateral dorsal horn, and the receptive field was then stimulated using a wide range of stimuli: brush, von Frey filaments (0.16, 0.4, 0.6, 1, 2, 4, 6, 8, 15, 26, 60 g), static ...