is the lack of appropriate mouse models. For instance, the commonly usedEµ:TCL1-driven murine CLL model is typicallyAtmandTrp53proficient12,13. Particularly B cell-specific deletion ofTrp53andAtmhas not been addressed in an autochthonous mouse model, thus far. WhenEµ:TCL1mice were crosse...
To provide novel insight into this question, we utilized tools with improved specificity, including intersectional mouse genetics, opto-tagged electrophysiological recordings, and optogenetic activation of Aβ-LTMRs, and we performed a battery of behavioral tests to probe mouse mechanical and thermal sens...
(or volts). Put the positive probe on TP3 and the negative probe on TP2. If you used a 10kΩ for R1, as indicated in the BOM, you should read a voltage in the single of millivolts. If you have something much higher, especially voltages above 20mV, then you likely have an issue...
【产品名称】 通用名称: 鼠源性成分(Mouse)荧光PCR检测试剂盒 Name :Mouse origin component (Mouse) nucleic acid detection kit (PCR- fluorescence probe method) 【包装规格】 48T/盒 鼠源性成分(Mouse)荧光PCR
三、Probe qPCR 反应(20μL 体系 ,在样品制备室进行) 9. 如果做定量分析并且只做 1 次重复 ,则标记 N+9 个 PCR 管 ,其中 N+2 个 用于上步得到的 N+2 个样品 , 1 个用于 PCR 阴性对照(用水做模板) ,6个用于标准曲线。 如果做定性分析,并且只做 1 次重复,则标记 N+4 个 PCR管, ...
the kappa BP gave a much stronger signal. See the 1 sec exposure in the image. There seems to be a lot of confusion among users about what this probe actually is. Many refer to it as an antibody, but it isn't, it's a binding protein. Whether it is Protein L or something else ...
11 ssDNA probe@Au-Ni Nanowire [66] Fuel-Free Magnets Magnetic field MCF-7 NR Theranostics: miRNA-21 detection, DOX delivery 12 Au nanowires [87] Fuel-Free Ultrasound Acoustic field DC 2.4 cells, BMDCs of C57BL/6 mice NR Intracellular ovalbumin antigen delivery 13 Liposomes@Magnetococcus marinu...
Across many domains, researchers have used this to probe the antecedents and consequences of decisional conflict. In the same way as reaction time offers a more direct means to study cognitive accessibility, the relative pull of an unchosen option during mouse-tracking allows a potentially more ...
Fetal growth restriction (FGR) affects 5–10% of pregnancies, and can have serious consequences for both mother and child. Prevention and treatment are limited because FGR pathogenesis is poorly understood. Genetic studies implicate KIR and HLA genes in
An integrated systems genetics and omics toolkit to probe gene function. Cell Syst. 6, 90–102 (2018). This study shows the power of the large accumulated data sets in the BXD mouse genetic reference population to connect genotype with phenotypes, using a range of strategies including PheWAS,...